Accurate Models of Substrate Preferences of Post-Translational Modification Enzymes from a Combination of mRNA Display and Deep Learning
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DOI: 10.1101/2022.02.14.480467
Abstract: Promiscuous post-translational modification (PTM) enzymes often display non-obvious substrate preferences by acting on diverse yet well-defined sets of peptides and/or proteins. Thorough understanding of substrate fitness landscapes for promiscuous PTM enzymes is important because they… read more here.
Keywords: post translational; ptm enzymes; substrate preferences; deep learning ... See more keywords