The Methods Employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein-Protein Interactions (PPIs).
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-15950-4_10
Abstract: Mass Spectrometry (MS) has revolutionized the way we study biomolecules, especially proteins, their interactions and posttranslational modifications (PTM). As such MS has established itself as the leading tool for the analysis of PTMs mainly because… read more here.
Keywords: protein; analysis; mass; biology ... See more keywords
Ten-gram-scale preparation of PTMS-based monodisperse ORMOSIL nano- and microparticles and conversion to silica particles
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-018-4186-6
Abstract: AbstractMonodisperse organically modified silica (ORMOSIL) particles, with an average diameter ranging from 550 nm to 4.2 μm, were prepared at low temperature at a scale of about 10 g/batch by a simple one-step self-emulsion process. The reaction mixture… read more here.
Keywords: ptms based; ormosil particles; silica particles; reaction ... See more keywords
Urban street dust bound 24 potentially toxic metal/metalloids (PTMs) from Xining valley-city, NW China: Spatial occurrences, sources and health risks.
Sign Up to like & getrecommendations! Published in 2018 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.07.006
Abstract: Street dusts (SDs) were a significant tracer to understand the pollution status of potentially toxic metal/metalloids (PTMs) in local environment. In this study, a total of 157 SDs were collected in the valley-city of Xining, NW… read more here.
Keywords: risk; potentially toxic; ptms; toxic metal ... See more keywords
Proteome-wide profiling and mapping of post translational modifications in human hearts
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81986-y
Abstract: Post translational modifications (PTMs) are covalent modifications of proteins that can range from small chemical modifications to addition of entire proteins. PTMs contribute to regulation of protein function and thereby greatly increase the functional diversity… read more here.
Keywords: human hearts; modifications human; post translational; proteome wide ... See more keywords
A simple toolset to identify endogenous post-translational modifications for a target protein: a snapshot of the EGFR signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Bioscience Reports"
DOI: 10.1042/bsr20170919
Abstract: Identification of a novel post-translational modification (PTM) for a target protein, defining its physiologic role and studying its potential cross-talk with other PTMs is a challenging process. A set of highly sensitive tools termed as… read more here.
Keywords: egfr signaling; post translational; target protein; signaling pathway ... See more keywords
Andrographolide nanophytosomes exhibit enhanced cellular delivery and pro-apoptotic activities in HepG2 liver cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Drug Delivery"
DOI: 10.1080/10717544.2023.2174209
Abstract: Abstract Andrographolide (AG), a major active constituent of Andrographis paniculata, is known to hinder proliferation of several types of cancer cells. However, its poor solubility and cellular permeability restrict its use in clinical applications. In… read more here.
Keywords: cancer; liver cancer; enhanced cellular; ptms ... See more keywords
y-mtPTM: Yeast Mitochondrial Post-Translational Modification Database.
Sign Up to like & getrecommendations! Published in 2023 at "Genetics"
DOI: 10.1093/genetics/iyad087
Abstract: One powerful strategy of how to increase the complexity of cellular proteomes is through post-translational modifications (PTMs) of proteins. Currently there are approximately 400 types of PTMs, the different combinations of which yield a large… read more here.
Keywords: yeast mitochondrial; ptms; post translational; database ... See more keywords
Midgut microbiota diversity of potato tuber moth associated with potato tissue consumed
Sign Up to like & getrecommendations! Published in 2020 at "BMC Microbiology"
DOI: 10.1186/s12866-020-01740-8
Abstract: Background The potato tuber moth (PTM), Phthorimaea operculella (Zeller), is a worldwide pest that feeds on both the leaves and tubers of potato plants. PTM larvae can digest leaves, or tubers, resulting in serious damage… read more here.
Keywords: potato tuber; midgut; potato; tuber ... See more keywords
Novel post-translational modifications of human serum albumin.
Sign Up to like & getrecommendations! Published in 2022 at "Protein and peptide letters"
DOI: 10.2174/0929866529666220318152509
Abstract: AIM Identify novel post-translational modifications in human serum albumin. BACKGROUND Serum albumin is the most abundant protein in plasma, has many physiological functions, and is in contact with most of the cells and tissues of… read more here.
Keywords: serum albumin; translational modifications; ptms; post translational ... See more keywords
Lysine Acylation Modification Landscape of Brucella abortus Proteome and its Virulent Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.839822
Abstract: The myriad of posttranslational modifications (PTMs) of proteins that occur in all living cells are crucial to all kinds of biological processes. Brucella is an intracellular parasitic bacterium that can cause chronic diseases in both… read more here.
Keywords: abortus; ptms; biological processes; lysine acylation ... See more keywords
Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2020.595532
Abstract: Post-translational modifications (PTMs) on tau have long been recognized as affecting protein function and contributing to neurodegeneration. The explosion of information on potential and observed PTMs on tau provides an opportunity to better understand these… read more here.
Keywords: tau; post translational; tau function; ptms ... See more keywords