Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α‐actinin4 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28379
Abstract: Neural stem/progenitor cells (NSPCs) are a promising candidate for the cell‐replacement therapy after central nervous system (CNS) injury. However, the short of sufficient NSPCs migration and integration into the lesions is an essential challenge for… read more here.
Keywords: migration; stem progenitor; cspg; nspcs migration ... See more keywords
Vitamin B12 Regulates Glial Migration and Synapse Formation through Isoform-Specific Control of PTP-3/LAR PRTP Expression
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.02.113
Abstract: SUMMARY Vitamin B12 is known to play critical roles during the development and aging of the brain, and vitamin B12 deficiency has been linked to neurodevelopmental and degenerative disorders. However, the underlying molecular mechanisms of… read more here.
Keywords: vitamin b12; expression; glial migration; ptp ... See more keywords
Cyclophilin D regulation of the mitochondrial permeability transition pore.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in physiology"
DOI: 10.1016/j.cophys.2022.100486
Abstract: The opening of the mitochondrial permeability transition pore (PTP) has been proposed to play a critical role in activating cell death in many settings, including cardiac ischemia and reperfusion. Although the identity of pore forming… read more here.
Keywords: ptp; transition pore; mitochondrial permeability; permeability transition ... See more keywords
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103274
Abstract: Summary Internalized and ubiquitinated signaling receptors are silenced by their intraluminal budding into multivesicular bodies aided by the endosomal sorting complexes required for transport (ESCRT) machinery. HD-PTP, an ESCRT protein, forms complexes with ESCRT-0, -I… read more here.
Keywords: ptp escrt; endofin required; endosomal sorting; endofin ... See more keywords
A novel class of cardioprotective small-molecule PTP inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104548
Abstract: Ischemia/reperfusion (I/R) injury is mediated in large part by opening of the mitochondrial permeability transition pore (PTP). Consequently, inhibitors of the PTP hold great promise for the treatment of a variety of cardiovascular disorders. At… read more here.
Keywords: ptp opening; small molecule; cypd; novel class ... See more keywords
Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-23153-5
Abstract: The hippocampal mossy fiber synapse is a key synapse of the trisynaptic circuit. Post-tetanic potentiation (PTP) is the most powerful form of plasticity at this synaptic connection. It is widely believed that mossy fiber PTP… read more here.
Keywords: fiber; hippocampal mossy; mossy fiber; ptp ... See more keywords
Dicerium letterbox-shaped tetraphenolates: f-block complexes designed for two-electron chemistry.
Sign Up to like & getrecommendations! Published in 2019 at "Dalton transactions"
DOI: 10.1039/c9dt03291f
Abstract: Rare examples of molecular, dinuclear CeIII and PrIII complexes with robust Ln-coordination are accessible by use of the tetraphenolate pTP as a supporting, chelating O-donor ligand platform, pTP = [{2-(OC6H2R2-2,4)2CH}-C6H4-1,4]4- that favours the higher formal… read more here.
Keywords: chemistry; shaped tetraphenolates; letterbox shaped; ptp ... See more keywords
Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFNγ signaling
Sign Up to like & getrecommendations! Published in 2017 at "Oncoimmunology"
DOI: 10.1080/2162402x.2017.1321185
Abstract: ABSTRACT PTP1B and TC-PTP are highly related protein-tyrosine phosphatases (PTPs) that regulate the JAK/STAT signaling cascade essential for cytokine-receptor activation in immune cells. Here, we describe a novel immunotherapy approach whereby monocyte-derived dendritic cell (moDC)… read more here.
Keywords: ptp; ptp1b ptp; immunotherapy; dendritic cell ... See more keywords
Pretest probability for patients with suspected obstructive coronary artery disease: re-evaluating Diamond-Forrester for the contemporary era and clinical implications: insights from the PROMISE trial.
Sign Up to like & getrecommendations! Published in 2019 at "European heart journal cardiovascular Imaging"
DOI: 10.1093/ehjci/jey182
Abstract: AIMS To update pretest probabilities (PTP) for obstructive coronary artery disease (CAD ≥ 50%) across age, sex, and clinical symptom strata, using coronary computed tomography angiography (CTA) in a large contemporary population of patients with stable chest… read more here.
Keywords: obstructive coronary; esc ptp; coronary artery; prevalence cad ... See more keywords
Photochemical Tissue Passivation Attenuates AV Fistula Intimal Hyperplasia
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Surgery"
DOI: 10.1097/sla.0000000000002046
Abstract: Objective: We hypothesized that decreasing vein compliance would protect the vein against stretch injury and reduce intimal hyperplasia (IH). Background: Although arteriovenous fistulas (AVFs) are the criterion standard for vascular access, their effectiveness is limited… read more here.
Keywords: intimal hyperplasia; control; ptp treated; ptp ... See more keywords
An Extension to the Precision Time Protocol (PTP) to Enable the Detection of Cyber Attacks
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Industrial Informatics"
DOI: 10.1109/tii.2019.2943913
Abstract: The precision time protocol (PTP) is considered as one of the most favorable mechanisms for providing unified and precise time at the substation level in the smart grid. Nevertheless, PTP was shown to be vulnerable… read more here.
Keywords: time; extension; precision time; cyber attacks ... See more keywords