A mitochondrial phosphatase PTPMT1 is essential for the early development of silkworm, Bombyx mori.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.07.124
Abstract: Juvenile hormone (JH) plays important roles in the control of many biological processes in insects, such as development, reproduction, and polyphenism. JH is primarily produced in the corpora allata (CA) by specific JH biosynthetic enzymes… read more here.
Keywords: phosphatase; bombyx mori; silkworm bombyx; ptpmt1 ... See more keywords
Biallelic PTPMT1 variants disrupt cardiolipin metabolism and lead to a neurodevelopmental syndrome
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DOI: 10.1093/brain/awae268
Abstract: Abstract Primary mitochondrial diseases (PMDs) are among the most common inherited neurological disorders. They are caused by pathogenic variants in mitochondrial or nuclear DNA that disrupt mitochondrial structure and/or function, leading to impaired oxidative phosphorylation… read more here.
Keywords: biallelic ptpmt1; cardiolipin metabolism; ptpmt1; neurodevelopmental syndrome ... See more keywords