Inhibiting microRNA-142-5p improves learning and memory in Alzheimer’s disease rats via targeted regulation of the PTPN1-mediated Akt pathway
Sign Up to like & getrecommendations! Published in 2022 at "Brain research bulletin"
DOI: 10.1016/j.brainresbull.2022.02.016
Abstract: OBJECTIVE MicroRNAs (miRNAs) have been recognized as possible biomarkers for Alzheimer's disease (AD). MiR-142-5p has been reported to be abnormally expressed in brain tissues. However, the role of miR-142-5p in AD pathogenesis keeps unclear. This… read more here.
Keywords: mir 142; akt pathway; learning memory; ptpn1 ... See more keywords
Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic Pathology"
DOI: 10.1186/s13000-019-0919-9
Abstract: BackgroundProtein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the function and expression of the non-receptor PTPN1 on… read more here.
Keywords: cell growth; human neuroblastoma; expression; cell ... See more keywords