Protein tyrosine phosphatase non‐receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection
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DOI: 10.1111/tan.13706
Abstract: The PTPN22 gene encodes the lymphoid protein tyrosine phosphatase involved in regulation the immune response. The single nucleotide polymorphisms (SNPs) rs1217388, rs1310182, rs2476601, and rs2488457 are located within the PTPN22 gene. We investigated whether these… read more here.
Keywords: ptpn22 gene; acute cellular; transplant donors; rejection ... See more keywords
TiO2 nanoparticles abrogate the protective effect of the Crohn’s disease-associated variation within the PTPN22 gene locus
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DOI: 10.1136/gutjnl-2021-325911
Abstract: Objective Inflammatory bowel disease (IBD) is a multifactorial condition driven by genetic and environmental risk factors. A genetic variation in the protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene has been associated with autoimmune disorders… read more here.
Keywords: effect; disease; ptpn22; tio2 nanoparticles ... See more keywords