The liver-brain-gut neural arc maintains the Treg cell niche in the gut.
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2425-3
Abstract: The gut-brain axis, a reciprocal interaction between the central nervous system (CNS) and peripheral intestinal functions, is conceptually feasible from recent clinical and experimental evidence showing mutual interactions between the CNS and gut microbiota that… read more here.
Keywords: gut; arc; brain gut; liver brain ... See more keywords
Accumulation of pTreg cells is detrimental in late‐onset (aged) mouse model of multiple sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13630
Abstract: Although typically associated with onset in young adults, multiple sclerosis (MS) also attacks the elderly, which is termed late‐onset MS. The disease can be recapitulated and studied in a mouse model, experimental autoimmune encephalomyelitis (EAE).… read more here.
Keywords: treg; ptreg cells; onset; cns ... See more keywords