Reduction responsive liposomes based on paclitaxel-ss-lysophospholipid with high drug loading for intracellular delivery.
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DOI: 10.1016/j.ijpharm.2019.04.060
Abstract: In this report, a novel redox-responsive liposomes based on disulfide derivative paclitaxel-ss-lysophosphatidylcholine prodrug (PTX-ss-PC) with high PTX loading was developed for triggering drug release. First of all, PTX-ss-PC was synthesized by a facile esterification and… read more here.
Keywords: reduction; responsive liposomes; ptx; drug ... See more keywords