Preparation of Paclitaxel and Etoposide Co-loaded mPEG-PLGA Nanoparticles: an Investigation with Artificial Neural Network
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DOI: 10.1007/s12247-019-09419-y
Abstract: Purpose The main purpose of this study was to develop etoposide (ETP) and paclitaxel (PTX) co-loaded methoxy poly(ethylene glycol)-poly(lactic-co-glycolic acid) (mPEG-PLGA) nanoparticles (NPs) with optimized size to achieve co-delivery of ETP and PTX. In addition,… read more here.
Keywords: plga nanoparticles; loaded mpeg; plga; mpeg plga ... See more keywords
Improving antitumor outcomes for palliative intratumoral injection therapy through lecithin– chitosan nanoparticles loading paclitaxel– cholesterol complex
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DOI: 10.2147/ijn.s188667
Abstract: Background Intratumoral injection is a palliative treatment that aims at further improvement in the survival and quality of life of patients with advanced or recurrent carcinomas, or cancer patients with severe comorbidities or those with… read more here.
Keywords: ptx loaded; lcs nps; intratumoral injection; loaded lcs ... See more keywords
pH- and Ultrasound-Responsive Paclitaxel-Loaded Carboxymethyl Chitosan Nanodroplets for Combined Imaging and Synergistic Chemoradiotherapy
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DOI: 10.2147/ijn.s233669
Abstract: Background Synergistic chemoradiotherapy (CRT) has become a primary effective curative approach for many solid cancers. However, CRT is still associated with several obstacles, including the increases in side effects and systemic toxicity. Incorporating nanocarriers into… read more here.
Keywords: synergistic chemoradiotherapy; loaded nds; ultrasound responsive; combined imaging ... See more keywords