Articles with "ptx resistance" as a keyword



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TRPM2‐AS promotes paclitaxel resistance in prostate cancer by regulating FOXK1 via sponging miR‐497‐5p

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Published in 2022 at "Drug Development Research"

DOI: 10.1002/ddr.21924

Abstract: Chemoresistance seriously hinders the treatment efficiency of human cancers, including prostate cancer (PCa). Multiple long noncoding RNAs (lncRNAs) were involved in drug resistance in PCa. We aimed to explore the function of transient receptor potential… read more here.

Keywords: ptx resistant; mir 497; ptx; pca ... See more keywords
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MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis.

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Published in 2023 at "Journal of biochemical and molecular toxicology"

DOI: 10.1002/jbt.23380

Abstract: Chemoresistance remains a major obstacle to the treatment of esophageal cancer (EC). Exosome-mediated transfer of long noncoding RNAs (lncRNAs) has recently been unveiled to correlate with the regulation of drug resistance in EC. This study… read more here.

Keywords: ec109 cells; ptx resistance; miat; resistance ... See more keywords
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MiR-199a suppresses prostate cancer paclitaxel resistance by targeting YES1

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Published in 2017 at "World Journal of Urology"

DOI: 10.1007/s00345-017-2143-0

Abstract: PurposeProstate cancer chemoresistance is a major contributor to the poor survival of patients. MicroRNAs (miRNAs) play an important role in regulating cancer resistance. Here we aim to explore the role and mechanism of miR-199a in… read more here.

Keywords: ptx resistance; mir 199a; resistance; prostate cancer ... See more keywords
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CircSETDB1 contributes to paclitaxel resistance of ovarian cancer cells by sponging miR-508-3p and regulating ABCC1 expression

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Published in 2022 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000001465

Abstract: Ovarian cancer is a gynecological tumor with a poor prognosis. The chemotherapy failure and recurrence induced by paclitaxel (Ptx) resistance are the main reason for the failure of ovarian cancer treatment. In this study, we… read more here.

Keywords: resistance ovarian; ovarian cancer; mir 508; ptx resistance ... See more keywords
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Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells

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Published in 2020 at "OncoTargets and therapy"

DOI: 10.2147/ott.s240434

Abstract: Purpose Paclitaxel (PTX) is a first-line chemotherapeutic agent for treating ovarian cancer. However, PTX resistance has become a major obstacle in ovarian cancer therapy. The underlying mechanism associated with PTX resistance is still unclear. Patients… read more here.

Keywords: ptx resistance; ovarian cancer; cancer; tug1 ... See more keywords
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SOX2 regulates paclitaxel resistance of A549 non-small cell lung cancer cells via promoting transcription of ClC-3

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Published in 2022 at "Oncology Reports"

DOI: 10.3892/or.2022.8396

Abstract: Paclitaxel (PTX) is widely used in the treatment of non-small cell lung cancer (NSCLC). However, acquired PTX drug resistance is a major obstacle to its therapeutic efficacy and the underlying mechanisms are still unclear. The… read more here.

Keywords: ptx resistance; resistance a549; clc; resistance ... See more keywords