Articles with "ptx3" as a keyword



MicroRNA‐224 inhibition prevents progression of cervical carcinoma by targeting PTX3

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Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27370

Abstract: Cervical carcinoma is known as one of the most lethal and common conditions in women worldwide. Increasing evidence shows that microRNAs (miRs) may be involved in the pathogenesis of cervical carcinoma. This study investigates the… read more here.

Keywords: mir 224; progression cervical; cervical carcinoma; ptx3 ... See more keywords

Acute ethanol intoxication suppresses pentraxin 3 expression in a mouse sepsis model involving cecal ligation and puncture.

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Published in 2017 at "Alcohol"

DOI: 10.1016/j.alcohol.2017.04.003

Abstract: Acute ethanol intoxication impairs immunological reactions and increases the risk of sepsis; however, the underlying mechanism remains unclear. Pentraxin (PTX) 3 is a humoral pattern recognition receptor whose levels rapidly increase in response to inflammation.… read more here.

Keywords: sepsis; ethanol intoxication; ptx3; expression ... See more keywords

Reply: Pentraxin-3 and coronary artery disease

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Published in 2018 at "Experimental Gerontology"

DOI: 10.1016/j.exger.2018.01.004

Abstract: We appreciate the perspectives of Dr. Hudzik and colleagues on the potential clinical utility of Gensini score in our study (KorzonekSzlacheta et al., 2018; Guo et al., 2017). Gensini score is one premier tool for… read more here.

Keywords: artery disease; cad; coronary artery; ptx3 ... See more keywords

ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cells

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Published in 2019 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2019.110485

Abstract: As one of the members of the transforming growth factor-β (TGF-β) superfamily, activin A plays an important role in regulating follicular development and oocyte maturation. Pentraxin 3 (PTX3) is the key component that promotes the… read more here.

Keywords: ptx3 human; smad4; ptx3; expression ... See more keywords
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Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19

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Published in 2020 at "Nature Immunology"

DOI: 10.1038/s41590-020-00832-x

Abstract: Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity, involved in resistance to selected pathogens and in the regulation of inflammation 1 – 3 . The present study was designed to assess… read more here.

Keywords: long pentraxin; ptx3; covid; pentraxin ptx3 ... See more keywords

The Effect of Corrected Inflammation, Oxidative Stress and Endothelial Dysfunction on Fmd Levels in Patients with Selected Chronic Diseases: A Quasi-Experimental Study

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-65528-6

Abstract: While the pathophysiology of chronic disorders varies there are three basic mechanisms - inflammation, oxidative stress and endothelial dysfunction – that are common in many chronic diseases. However, the failure of these mechanisms to work… read more here.

Keywords: chronic diseases; selected chronic; fmd; ptx3 ... See more keywords

Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-89032-7

Abstract: Long pentraxin PTX3, a pattern recognition molecule involved in innate immune responses, is upregulated by pro-inflammatory stimuli, contributors to secondary damage in traumatic brain injury (TBI). We analyzed PTX3 involvement in mice subjected to controlled… read more here.

Keywords: long pentraxin; histopathology; ptx3; pentraxin ptx3 ... See more keywords

Pentraxin 3 promotes the osteoblastic differentiation of MC3T3-E1 cells through the PI3K/Akt signaling pathway

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Published in 2020 at "Bioscience Reports"

DOI: 10.1042/bsr20201165

Abstract: Abstract Osteoblast cells are responsible for synthesizing new bone tissue, and determining how to control osteoblastic differentiation is vital to the treatment of osteoporosis. In the present study, we show that pentraxin 3 (PTX3) signaling… read more here.

Keywords: differentiation; differentiation mc3t3; ptx3; osteoblastic differentiation ... See more keywords

The natural immune molecules urinary Tamm–Horsfall protein and pentraxin 3 as predictors for recurrent urinary tract infection severity: a single-center self-control study

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Published in 2025 at "Renal Failure"

DOI: 10.1080/0886022x.2024.2449574

Abstract: Abstract Objective The innate immune defense plays a pivotal role in protecting the urinary tract from uropathogenic invasion and maintaining immune homeostasis. Dysregulation of the innate immune system can result in recurrent urinary tract infections… read more here.

Keywords: thp; group; urinary tract; ruti ... See more keywords

PRMT1 driven PTX3 regulates ferritinophagy in glioma.

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Published in 2023 at "Autophagy"

DOI: 10.1080/15548627.2023.2165757

Abstract: Mutations in the Krebs cycle enzyme IDH1 (isocitrate dehydrogenase (NADP(+)) 1) are associated with better prognosis in gliomas. Though IDH1 mutant (IDH1R132H) tumors are characterized by their antiproliferative signatures maintained through hypermethylation of DNA and… read more here.

Keywords: idh1 mutant; idh1; ptx3; prmt1 ... See more keywords

PTX3 Regulates miR-21 Expression and Secretion in Brown Adipocytes During Lipopolysaccharide-induced Inflammation (P21-072-19).

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Published in 2019 at "Current developments in nutrition"

DOI: 10.1093/cdn/nzz041.p21-072-19

Abstract: Objectives Metabolic endotoxemia is known to induce systemic inflammation and adipose tissue dysfunction during obesity. Pentraxin 3 (PTX3), a member of the pentraxin family can be induced by inflammatory stimuli in adipocytes. However, how PTX3… read more here.

Keywords: expression; ptx3; expression secretion; brown adipocytes ... See more keywords