Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation
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DOI: 10.1093/nar/gkac482
Abstract: Abstract We have investigated the function of human topoisomerase 1 (TOP1) in regulation of G-quadruplex (G4) formation in the Pu27 region of the MYC P1 promoter. Pu27 is among the best characterized G4 forming sequences… read more here.
Keywords: promoter; myc promoter; pu27; formation ... See more keywords