Dual‐mechanism gastroretentive drug delivery system loaded with an amorphous solid dispersion prepared by hot‐melt extrusion
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.02.040
Abstract: &NA; In the present study, we aimed to prepare a gastroretentive drug delivery system that would be both highly resistant to gastric emptying via multiple mechanisms and would also potentially induce in situ supersaturation. The… read more here.
Keywords: pubchem cid; melt extrusion; delivery system; drug delivery ... See more keywords
Artichoke (Cynara cardunculus L. var. scolymus) waste as a natural source of carbonyl trapping and antiglycative agents.
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DOI: 10.1016/j.foodres.2017.08.007
Abstract: The role of polyphenolic compounds extractable from artichoke solid wastes in the formation of advanced glycation end products (AGEs) was studied. Outer bracts and stems were extracted using different water-ethanol mixtures and HPLC-DAD analyses indicated… read more here.
Keywords: pubchem cid; pubchem; antiglycative agents; acid pubchem ... See more keywords
Flavonoid compounds as reversing agents of the P-glycoprotein-mediated multidrug resistance: An in vitro evaluation with focus on antiepileptic drugs.
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DOI: 10.1016/j.foodres.2017.10.010
Abstract: The pharmacoresistance to antiepileptic drugs (AEDs) remains a major unsolved therapeutic need. The overexpression of multidrug transporters, as the P-glycoprotein (P-gp), at the level of the blood-brain barrier of epileptic patients has been suggested as… read more here.
Keywords: antiepileptic drugs; pubchem cid; pubchem; multidrug resistance ... See more keywords
Hepatoma-derived growth factor enhances osteoblastic transformation of rat aortic vascular smooth muscle cells in vitro.
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DOI: 10.1016/j.lfs.2020.117964
Abstract: AIMS Vascular smooth muscle cells (VSMCs) are important regulators of vascular functions and their conversion to osteoblasts is a key to development of vascular calcification. This study aimed to characterize in vitro effect of hepatoma-derived… read more here.
Keywords: pubchem cid; hdgf; smooth muscle; factor ... See more keywords