Chronic estrus disrupts uterine gland development and homeostasis.
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DOI: 10.1210/endocr/bqac011
Abstract: Female mice homozygous for an engineered Gnrhr E90K mutation have reduced gonadotropin-releasing hormone signaling, leading to infertility. Their ovaries have numerous antral follicles but no corpora lutea, indicating a block to ovulation. These mutants have… read more here.
Keywords: development; pubertal uterine; post pubertal; gland development ... See more keywords