Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface.
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DOI: 10.1016/j.bioorg.2020.103978
Abstract: In the present work, the oxoaporphine alkaloid dicentrinone was isolated, for the first time, from leaves of Ocotea puberula (Lauraceae). This alkaloid exhibited antiparasitic activity against trypomastigote forms of Trypanosoma cruzi (IC50 of 16.4 ± 1.7 μM), similar… read more here.
Keywords: dicentrinone; cell membrane; puberula lauraceae; ocotea puberula ... See more keywords