KCNE1 tunes the sensitivity of KV7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site
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DOI: 10.7554/elife.37257
Abstract: The voltage-gated potassium channel KV7.1 and the auxiliary subunit KCNE1 together form the cardiac IKs channel, which is a proposed target for future anti-arrhythmic drugs. We previously showed that polyunsaturated fatty acids (PUFAs) activate KV7.1… read more here.
Keywords: polyunsaturated fatty; binding site; fatty acids; kv7 ... See more keywords