Omega‐3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2017.12.005
Abstract: Abstract The purpose of this study was to evaluate the neuroprotective effects of omega‐3 polyunsaturated fatty acid (ω3‐PUFA) supplementation, alone or in combination with timolol eye drops, in a mouse model of hereditary glaucoma. DBA/2J… read more here.
Keywords: pufa; timolol; hereditary glaucoma; pufas ... See more keywords
Effects of the combination of ω-3 PUFAs and proanthocyanidins on the gut microbiota of healthy rats.
Sign Up to like & getrecommendations! Published in 2017 at "Food research international"
DOI: 10.1016/j.foodres.2017.04.024
Abstract: ω-3 Polyunsaturated fatty acids (PUFAs) reduce risk factors for cardiovascular diseases (CVD) and other pathologies that involve low-grade inflammation. They have recently been shown to exert complementary functional effects with proanthocyanidins. As the reduction of… read more here.
Keywords: combination; gse; pufas proanthocyanidins; pufas ... See more keywords
Red blood cell polyunsaturated fatty acids and mortality in the Women's Health Initiative Memory Study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2016.12.013
Abstract: BACKGROUND The prognostic value of circulating polyunsaturated fatty acid (PUFA) levels is unclear. OBJECTIVES To determine the associations between red blood cell (RBC) PUFA levels and risk for death. METHODS This prospective cohort study included 6501… read more here.
Keywords: pufa; study; mortality; pufas ... See more keywords
High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis–inactivated Δ6-fatty acid desaturase–deficient mouse
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2021.101335
Abstract: Objective An increased ω6/ω3-polyunsaturated fatty acid ratio in the current Western diet is regarded as a critical epigenetic nutritional factor in the pathogenesis of several human lifestyle diseases, metabolic syndrome, cardiovascular disease, the central nervous… read more here.
Keywords: synthesis; fatty acid; pufas; fads2 ... See more keywords
Dietary PUFAs drive diverse system-level changes in lipid metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2022.101457
Abstract: Objective Polyunsaturated fatty acid (PUFA) supplements have been trialled as a treatment for a number of conditions and produced a variety of results. This variety is ascribed to the supplements, that often comprise a mixture… read more here.
Keywords: system level; lipid metabolism; changes lipid; metabolism ... See more keywords
STANDARDIZATION OF ROUTINE QUANTIFICATION OF POLYUNSATURATED ACIDS IN PEDIATRIC TOTAL PARENTERAL NUTRITION
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition"
DOI: 10.1016/j.nut.2020.110916
Abstract: Plasma and erythrocyte PUFAs are useful in clinical practice to optimize the parenteral nutrition therapy. The aim of this study was the definition of pediatric PUFAs reference ranges to follow-up patients with IICB. We validated… read more here.
Keywords: parenteral nutrition; standardization routine; reference ranges; plasma ... See more keywords
Targeting neuroinflammation: The therapeutic potential of omega-3 PUFAs in substance abuse.
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition"
DOI: 10.1016/j.nut.2020.111058
Abstract: Substance abuse is a chronic relapsing disorder that results in serious health and socioeconomic issues worldwide. Addictive drugs induce long-lasting morphologic and functional changes in brain circuits and account for the formation of compulsive drug-seeking… read more here.
Keywords: addiction; substance abuse; neuroinflammation; pufas ... See more keywords
Polyunsaturated fatty acids and suicide risk in mood disorders: A systematic review
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2016.11.007
Abstract: ABSTRACT Deficiency of omega‐3 polyunsaturated fatty acids (PUFAs) and an alteration between the ratio of omega‐3 and omega‐6 PUFAs may contribute to the pathogenesis of bipolar disorder and unipolar depression. Recent epidemiological studies have also… read more here.
Keywords: risk; polyunsaturated fatty; fatty acids; pufas ... See more keywords
Early biochemical observations point to nutritional strategies to manage non-alcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical science"
DOI: 10.1042/cs20220380
Abstract: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease globally. The first stage of NAFLD is steatosis, the accumulation of triacylglycerols within hepatocytes. Inflammation and oxidative stress both contribute to progression to more… read more here.
Keywords: alcoholic fatty; non alcoholic; fatty liver; oxidative stress ... See more keywords
The Effect of Oral Administration of PUFAs on the Matrix Metalloproteinase Expression in Gastric Adenocarcinoma Patients Undergoing Chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2018.1506494
Abstract: Abstract Objective: Gastric cancer is the third-leading cause of cancer-related mortality and the fifth most common cancer globally. Polyunsaturated fatty acids (PUFAs) are considered as functional ingredients that improve the efficacy of chemotherapeutic drugs. The… read more here.
Keywords: gastric cancer; group; pufas; effect ... See more keywords
Effects of Polyunsaturated Fatty Acids on Colorectal Cancer Patients: A Meta-Analysis of Randomized Controlled Trials
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2022.2145319
Abstract: Abstract This study aimed to investigate the effects of polyunsaturated fatty acids (PUFAs) on patients with colorectal cancer (CRC). Electronic databases such as PubMed and Web of Science were searched. Studies on the application of… read more here.
Keywords: cancer; polyunsaturated fatty; pufas; colorectal cancer ... See more keywords