DPV pUL15 possesses a potential NLS, which is important for the location of the terminase complex and for viral proliferation and genome cleavage
Sign Up to like & getrecommendations! Published in 2025 at "Veterinary Research"
DOI: 10.1186/s13567-024-01420-9
Abstract: In herpesvirus, the terminase subunit pUL15 is involved in cleavage of the viral genome concatemers in the nucleus. Previous studies have shown that herpes simplex virus 1 (HSV-1) pUL15 can enter the nucleus without other… read more here.
Keywords: nls; terminase; genome; pul15 ... See more keywords
Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom9100603
Abstract: Approximately 80% of adults are infected with a member of the herpesviridae family. Herpesviruses establish life-long latent infections within neurons, which may reactivate into lytic infections due to stress or immune suppression. There are nine… read more here.
Keywords: dna; pul15; packaging; herpes simplex ... See more keywords