Accelerated conversion of atrial fibrillation to normal sinus rhythm by pulmonary delivery of flecainide acetate in a porcine model.
Sign Up to like & getrecommendations! Published in 2018 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2018.06.036
Abstract: BACKGROUND Pulmonary delivery of antiarrhythmic agents has the potential to increase rapidly targeted drug concentrations in pulmonary veins and left atrium to terminate atrial fibrillation (AF). OBJECTIVE We evaluated the efficacy of flecainide administered via… read more here.
Keywords: atrial fibrillation; normal sinus; pulmonary delivery; sinus rhythm ... See more keywords
Pulmonary delivery of therapeutic proteins based on zwitterionic chitosan-based nanocarriers for treatment on bleomycin-induced pulmonary fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.04.066
Abstract: Nanoparticle-based pulmonary delivery of protein therapeutics provides a promising approach for improving protein bioavailability to treat either local or systemic diseases, however high-efficient nanocarrier is a great challenge. Here, biomimetic phosphorylcholine-chitosan nanoparticles (PCCs-NPs) taking advantages… read more here.
Keywords: bleomycin induced; fibrosis; pulmonary delivery; delivery ... See more keywords
Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent
Sign Up to like & getrecommendations! Published in 2020 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2020.109858
Abstract: Abstract Coronavirus disease outbreak caused a severe public health burden all over the world. Salinomycin (SAL) is a broad-spectrum antibiotic that had drawn attention in selective targeting of cancer and viral infections. Recent drug screen… read more here.
Keywords: lipid carriers; antiviral agent; pulmonary delivery; nanostructured lipid ... See more keywords
Pulmonary Delivery of Theranostic Nanoclusters for Lung Cancer Ferroptosis with Enhanced Chemodynamic/Radiation Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.1c03786
Abstract: Inefficient tumor accumulation and penetration remain as the main challenges to therapy efficacy of lung cancer. Local delivery of smart nanoclusters can increase drug penetration and provide superior antitumor effects than systemic routes. Here, we… read more here.
Keywords: cancer; ferroptosis; therapy; lung cancer ... See more keywords
Pulmonary delivery of mucosal nanovaccines
Sign Up to like & getrecommendations! Published in 2021 at "Nanoscale"
DOI: 10.1039/d1nr06512b
Abstract: Mucosal vaccination can elicit both systemic and mucosal immunity, and therefore has the potential to not only treat mucosal immune diseases, prevent the pathogen infection at the mucosal entry sites, but also treat distant or… read more here.
Keywords: immune; delivery mucosal; mucosal nanovaccines; pulmonary delivery ... See more keywords
Pulmonary delivery of resveratrol-β-cyclodextrin inclusion complexes for the prevention of zinc chloride smoke-induced acute lung injury
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2048135
Abstract: Abstract Smoke bombs are often used in military/fire training, which can produce a large amount of zinc chloride (ZnCl2) smoke. Inhalation of ZnCl2 smoke usually causes acute lung injury (ALI) that would likely develop to… read more here.
Keywords: smoke; prevention; smoke induced; lung ... See more keywords
Critical Parameters for Particle-Based Pulmonary Delivery of Chemotherapeutics.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of aerosol medicine and pulmonary drug delivery"
DOI: 10.1089/jamp.2017.1382
Abstract: Targeted delivery of chemotherapeutics through the respiratory system is a potential approach to improve drug accumulation in the lung tumor, while decreasing their negative side effects. However, elimination by the pulmonary clearance mechanisms, including the… read more here.
Keywords: system; pulmonary delivery; delivery; drug ... See more keywords
Pulmonary Delivery of Therapeutic and Diagnostic Gases.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of aerosol medicine and pulmonary drug delivery"
DOI: 10.1089/jamp.2017.1431
Abstract: The 21st Congress for the International Society for Aerosols in Medicine included, for the first time, a session on Pulmonary Delivery of Therapeutic and Diagnostic Gases. The rationale for such a session within ISAM is… read more here.
Keywords: medicine; pulmonary delivery; diagnostic gases; delivery ... See more keywords
Pulmonary Delivery of Isoniazid in Nanogel-Loaded Chitosan Hybrid Microparticles for Inhalation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of aerosol medicine and pulmonary drug delivery"
DOI: 10.1089/jamp.2018.1460
Abstract: PURPOSE Inhalable pulmonary delivery of isoniazid (INH) may improve the efficacy and reduce drug resistance. METHOD INH-loaded chitosan microparticles (Cs-Mps-1-3) were prepared as an inhalable carrier for the previously prepared INH-loaded polyvinylpyrrolidone/polyitaconic acid nanoparticles (NPs)… read more here.
Keywords: inh; loaded chitosan; delivery isoniazid; pulmonary delivery ... See more keywords
Curcumin Acetate Nanocrystals for sustained Pulmonary Delivery: Preparation, Characterization and In Vivo Evaluation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2017.2326
Abstract: The main objective of this study was to test the hypothesis that inhaled nanocrystals of a highly lipophilic drug could be used as a novel approach for producing sustained pulmonary delivery. Curcumin acetate, an ester… read more here.
Keywords: sustained pulmonary; pulmonary delivery; curcumin acetate; curcumin ... See more keywords
Pulmonary Delivery of Triptorelin Loaded in Pluronic Based Nanomicelles in Rat Model.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug delivery"
DOI: 10.2174/1567201815666180209113735
Abstract: INTRODUCTION Triptorelin, the synthetic analog of gonadotrophin-releasing hormone, is used for the treatment of sex hormone dependent diseases via parenteral administration. The aim of the present study was to investigate the possibility of triptorelin pulmonary… read more here.
Keywords: triptorelin; pulmonary delivery; delivery; solution ... See more keywords