Mitochondrial dynamics in pulmonary disease: Implications for the potential therapeutics
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31370
Abstract: Mitochondria are dynamic organelles that continuously undergo fusion/fission to maintain normal cell physiological activities and energy metabolism. When mitochondrial dynamics is unbalanced, mitochondrial homeostasis is broken, thus damaging mitochondrial function. Accumulating evidence demonstrates that impairment… read more here.
Keywords: disease; pulmonary diseases; mitochondrial dynamics; dynamics pulmonary ... See more keywords
Editorial for “Validation of Automated Perfusion‐Weighted Phase‐Resolved Functional Lung (PREFUL)‐MRI in Patients With Pulmonary Diseases”
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27093
Abstract: The amount of arterial blood flow to a tissue, defined as perfusion, is closely related to the supply of oxygen and nutrients to an organ and consequently to its function. Perfusion can be altered in… read more here.
Keywords: dce mri; respiratory cardiac; perfusion; pulmonary diseases ... See more keywords
Preclinical evidence using synthetic compounds and natural products indicates that AMPK represents a potential pharmacological target for the therapy of pulmonary diseases
Sign Up to like & getrecommendations! Published in 2024 at "Medicinal Research Reviews"
DOI: 10.1002/med.22014
Abstract: Adenosine 5′‐monophosphate (AMP)‐activated protein kinase (AMPK) is a highly conserved eukaryotic enzyme discovered as a key regulator of cellular energy homeostasis, with anti‐inflammation, antioxidative stress, anticancer, and antifibrosis beneficial effects. AMPK is dysregulated in human… read more here.
Keywords: pulmonary diseases; synthetic compounds; evidence using; using synthetic ... See more keywords
BRONCHIAL ASTHMA AND OTHER CHRONIC OBSTRUCTIVE PULMONARY DISEASES.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric pulmonology"
DOI: 10.1002/ppul.25963
Abstract: This article is protected by copyright. All rights reserved. read more here.
Keywords: obstructive pulmonary; chronic obstructive; pulmonary diseases; bronchial asthma ... See more keywords
Innate Immune Responses and Pulmonary Diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-68748-9_4
Abstract: Innate immunity is the first defense line of the host against various infectious pathogens, environmental insults, and other stimuli causing cell damages. Upon stimulation, pattern recognition receptors (PRRs) act as sensors to activate innate immune… read more here.
Keywords: immune responses; pulmonary diseases; activation; innate immune ... See more keywords
Kinase inhibitors in the treatment of obstructive pulmonary diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2020.03.005
Abstract: Chronic pulmonary diseases, including chronic obstructive pulmonary disease (COPD) and asthma, are major causes of death and reduced quality of life. Characteristic of chronic pulmonary disease is excessive lung inflammation that occurs in response to… read more here.
Keywords: kinase inhibitors; chronic pulmonary; obstructive pulmonary; pulmonary diseases ... See more keywords
Detecting pulmonary diseases using deep features in X-ray images
Sign Up to like & getrecommendations! Published in 2021 at "Pattern Recognition"
DOI: 10.1016/j.patcog.2021.108081
Abstract: COVID-19 leads to radiological evidence of lower respiratory tract lesions, which support analysis to screen this disease using chest X-ray. In this scenario, deep learning techniques are applied to detect COVID-19 pneumonia in X-ray images,… read more here.
Keywords: detecting pulmonary; diseases using; deep learning; pulmonary diseases ... See more keywords
In Vivo Fate of CXCR2-Overexpressing Mesenchymal Stromal/Stem Cells in Pulmonary Diseases Monitored by Near-Infrared Region 2 Imaging.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c01741
Abstract: Lung-associated diseases pose a huge threat to human society. Mesenchymal stromal/stem cells (MSCs) hold great promise in the treatment of pulmonary diseases through cell transdifferentiation, paracrine factors, immune regulation, EV secretion, and drug loading. However,… read more here.
Keywords: mesenchymal stromal; infrared region; pulmonary diseases; near infrared ... See more keywords
Inhalable Metal-Organic Frameworks: A Promising Delivery Platform for Pulmonary Diseases Treatment.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.4c16873
Abstract: Inhalation delivery, offering a direct pathway for administering drugs to the lungs in the form of dry powders or aerosols, stands out as an optimal approach for the localized treatment of pulmonary diseases. However, the… read more here.
Keywords: pulmonary diseases; treatment; delivery; inhalation ... See more keywords
Pulmonary diseases accurate recognition using adaptive multiscale feature fusion in chest radiography
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-13479-1
Abstract: Pulmonary disease can severely impair respiratory function and be life-threatening. Accurately recognizing pulmonary diseases in chest X-ray images is challenging due to overlapping body structures and the complex anatomy of the chest. We propose an… read more here.
Keywords: adaptive multiscale; pulmonary diseases; fusion; feature fusion ... See more keywords
The mechanisms of kidney–lung interactions in chronic kidney disease-associated pulmonary diseases: A two-sample Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2025 at "Renal Failure"
DOI: 10.1080/0886022x.2025.2578837
Abstract: Abstract Background The aim of this study was to investigate the relationship between chronic kidney disease and pulmonary diseases, and explore the mechanisms of kidney-lung interactions. Methods Two-sample Mendelian randomization (MR) was performed to explore… read more here.
Keywords: pulmonary diseases; lung; kidney disease; chronic kidney ... See more keywords