Tracing micro and nanoplastics toxicity in human pulmonary fibroblasts through integrated Raman and transcriptomic analyses
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DOI: 10.1038/s41598-025-22947-7
Abstract: Inhaled micro- and nanoplastics can reach the distal regions of the lungs, where their elimination is limited due to the lack of efficient clearance mechanisms. Although polystyrene particles have been detected in human lung tissue,… read more here.
Keywords: micro nanoplastics; internalization; pulmonary fibroblasts; human pulmonary ... See more keywords
10 Am2/imd secretion from human pulmonary smooth muscle cells and pulmonary fibroblasts is augmented in response to mechanical stretch
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DOI: 10.1136/heartjnl-2018-scf.20
Abstract: Introduction Pulmonary hypertension (PHT) is a severe life-limiting condition resulting in progressive shortness of breath, exercise intolerance and heart failure. PHT is defined by increased mean pulmonary arterial pressure (PAP) ≥25 mmHg at rest, and has… read more here.
Keywords: secretion; stretch; pulmonary fibroblasts; am2 imd ... See more keywords
TRPV4 Stimulation Releases ATP via Pannexin Channels in Human Pulmonary Fibroblasts
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DOI: 10.1165/rcmb.2017-0413oc
Abstract: &NA; We previously described several ionic conductances in human pulmonary fibroblasts, including one activated by two structurally distinct TRPV4 (transient receptor potential, vanilloid‐type, subtype 4)‐channel agonists: 4&agr;PDD (4&agr;‐phorbol‐12,13‐didecanoate) and GSK1016790A. However, the TRPV4‐activated current exhibited… read more here.
Keywords: pannexin channels; pulmonary fibroblasts; atp via; human pulmonary ... See more keywords