10 Am2/imd secretion from human pulmonary smooth muscle cells and pulmonary fibroblasts is augmented in response to mechanical stretch
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DOI: 10.1136/heartjnl-2018-scf.20
Abstract: Introduction Pulmonary hypertension (PHT) is a severe life-limiting condition resulting in progressive shortness of breath, exercise intolerance and heart failure. PHT is defined by increased mean pulmonary arterial pressure (PAP) ≥25 mmHg at rest, and has… read more here.
Keywords: secretion; stretch; pulmonary fibroblasts; am2 imd ... See more keywords
TRPV4 Stimulation Releases ATP via Pannexin Channels in Human Pulmonary Fibroblasts
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DOI: 10.1165/rcmb.2017-0413oc
Abstract: &NA; We previously described several ionic conductances in human pulmonary fibroblasts, including one activated by two structurally distinct TRPV4 (transient receptor potential, vanilloid‐type, subtype 4)‐channel agonists: 4&agr;PDD (4&agr;‐phorbol‐12,13‐didecanoate) and GSK1016790A. However, the TRPV4‐activated current exhibited… read more here.
Keywords: pannexin channels; pulmonary fibroblasts; atp via; human pulmonary ... See more keywords