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Published in 2020 at "Human gene therapy"
DOI: 10.1089/hum.2020.166
Abstract: The lung has long been a target for gene therapy, yet efficient delivery and phenotypic disease correction has remained challenging. While there have been significant advancements in gene therapies of other organs, including the development…
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Keywords:
new directions;
gene therapy;
directions pulmonary;
pulmonary gene ... See more keywords
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Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13091377
Abstract: In this work, we propose chitosan (CS)-based nanocapsules (NCs) for pulmonary gene delivery. Hyaluronic acid (HA) was incorporated in the NCs composition (HA/CS NCs) aiming to promote gene transfection in the lung epithelium. NCs were…
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Keywords:
delivery;
chitosan based;
pulmonary gene;
gene delivery ... See more keywords