Assessment of the nitrofen model of congenital diaphragmatic hernia and of the dysregulated factors involved in pulmonary hypoplasia
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Surgery International"
DOI: 10.1007/s00383-018-4375-5
Abstract: PurposeTo study pulmonary hypoplasia (PH) associated with congenital diaphragmatic hernia (CDH), investigators have been employing a fetal rat model based on nitrofen administration to dams. Herein, we aimed to: (1) investigate the validity of the… read more here.
Keywords: congenital diaphragmatic; diaphragmatic hernia; pulmonary hypoplasia; model ... See more keywords
Pulmonary Hypoplasia in a Young Adult.
Sign Up to like & getrecommendations! Published in 2018 at "Archivos de bronconeumologia"
DOI: 10.1016/j.arbres.2017.08.003
Abstract: A 27-year-old Moroccan man, living in Spain for 9 years, with no known toxic habits or significant medical history. He was diagnosed incidentally with left pulmonary hypoplasia after consulting for non-specific chest pain. A marked… read more here.
Keywords: hypoplasia young; young adult; pulmonary hypoplasia; lung ... See more keywords
Mortality trends in neonatal ECMO for pulmonary hypoplasia: A review of the Extracorporeal Life Support Organization database from 1981 to 2016.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2020.09.005
Abstract: BACKGROUND The purpose of this review is to provide ECMO outcome data for medical personnel who counsel families of patients with pulmonary hypoplasia (PH), often secondary to renal abnormalities. We report diagnoses and outcomes associated… read more here.
Keywords: pulmonary hypoplasia; mortality; database; 1981 2016 ... See more keywords
Pulmonary Hypoplasia Induced by Oligohydramnios: Findings from Animal Models and a Population-Based Study.
Sign Up to like & getrecommendations! Published in 2017 at "Pediatrics and neonatology"
DOI: 10.1016/j.pedneo.2016.04.001
Abstract: Pulmonary hypoplasia is a substantial cause of death in newborn infants, and oligohydramnios is one of the most commonly associated abnormalities. Lung growth is influenced by physical factors such as the intrauterine space, lung liquid… read more here.
Keywords: pulmonary hypoplasia; population based; lung; based study ... See more keywords
A rare association of left pulmonary artery sling with right pulmonary hypoplasia and total anomalous pulmonary venous connection
Sign Up to like & getrecommendations! Published in 2019 at "Cardiology in the Young"
DOI: 10.1017/s1047951119000131
Abstract: Abstract We present the second reported case of left pulmonary artery sling with dextrocardia, right pulmonary hypoplasia, and total pulmonary venous connection in a fetus. This case highlights the importance of the determination of pulmonary… read more here.
Keywords: left pulmonary; pulmonary artery; right pulmonary; pulmonary hypoplasia ... See more keywords
Treatment with Amniotic Fluid Stem Cell Extracellular Vesicles Promotes Fetal Lung Branching and Cell Differentiation at Canalicular and Saccular Stages in Experimental Pulmonary Hypoplasia Secondary to Congenital Diaphragmatic Hernia
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szac063
Abstract: Abstract Pulmonary hypoplasia secondary to congenital diaphragmatic hernia (CDH) is characterized by impaired branching morphogenesis and differentiation. We have previously demonstrated that administration of extracellular vesicles derived from rat amniotic fluid stem cells (AFSC-EVs) rescues… read more here.
Keywords: cell; pulmonary hypoplasia; lung; hypoplasia secondary ... See more keywords
Buccal carcinoma associated with adult congenital pulmonary hypoplasia: A case report and literature review
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032142
Abstract: Rationale: Congenital pulmonary hypoplasia is a relatively rare lung malformation. The disease is usually identified in the neonatal period or early childhood. Most affected patients die of respiratory insufficiency after birth. Mild congenital dysplasia is… read more here.
Keywords: buccal carcinoma; hypoplasia; pulmonary hypoplasia; report ... See more keywords
Siblings with lethal primary pulmonary hypoplasia and compound heterozygous variants in the AARS2 gene: further delineation of the phenotypic spectrum
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor Molecular Case Studies"
DOI: 10.1101/mcs.a003699
Abstract: Variants in the mitochondrial alanyl-tRNA synthetase 2 gene AARS2 (OMIM 612035) are associated with infantile mitochondrial cardiomyopathy or later-onset leukoencephalopathy with premature ovarian insufficiency. Here, we report two newborn siblings who died soon after birth… read more here.
Keywords: pulmonary hypoplasia; primary pulmonary; phenotypic spectrum; gene ... See more keywords
Nitric Oxide in Pulmonary Hypoplasia: Results from the European iNO Registry
Sign Up to like & getrecommendations! Published in 2019 at "Neonatology"
DOI: 10.1159/000501800
Abstract: Objectives: The aim of this work was to describe treatment response and outcome data for preterm infants with pulmonary hypoplasia treated with inhaled nitric oxide (iNO). We hypothesised that an acute oxygenation response to iNO… read more here.
Keywords: response; pulmonary hypoplasia; oxygenation; ino ... See more keywords
Evaluation of Pulmonary Hypoplasia in Various Congenital Anomalies with a Comparison of Two Conventional Methods of Assessment: Radial Alveolar Count (RAC) and Lung Weight: Body Weight Ratio (LBW).
Sign Up to like & getrecommendations! Published in 2021 at "Turk patoloji dergisi"
DOI: 10.5146/tjpath.2021.01521
Abstract: OBJECTIVE Pulmonary hypoplasia is common in the perinatal period and causes death in newborn infants. It is commonly associated with a number of malformation syndromes. Various parameters are used to estimate pulmonary hypoplasia at fetal… read more here.
Keywords: lung weight; pulmonary hypoplasia; ratio; rac ... See more keywords
Evaluation of Relative Frequency of Pulmonary Hypoplasia and Various Anomalies Associated with Pulmonary Hypoplasia in Fetal Autopsy Study.
Sign Up to like & getrecommendations! Published in 2022 at "Turk patoloji dergisi"
DOI: 10.5146/tjpath.2022.01594
Abstract: OBJECTIVE Pulmonary hypoplasia (PH) is one of the commonest causes of neonatal morbidity and mortality. The suggested diagnostic criteria for PH are the Lung Weight:Body Weight (LW:BW) ratio ≤ 0.012 and/or Radial Alveolar Count (RAC)… read more here.
Keywords: pulmonary hypoplasia; rac; fetal autopsy; study ... See more keywords