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Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2092-4
Abstract: Pulmonary Langerhans cell histiocytosis (PLCH) is a rare, smoking-related histiocytic disorder with variable clinical symptoms. Like in other non-pulmonary Langerhans cell proliferations, PLCH has recently been shown to harbour BRAF V600E mutations in a significant…
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Keywords:
langerhans cell;
braf v600e;
braf;
pulmonary langerhans ... See more keywords
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Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000015240
Abstract: Rationale: Isolated pulmonary Langerhans cell histiocytosis (PLCH) is rare in adults. The gold standard diagnosis requires surgical lung biopsy. However, few cases have been diagnosed with transbronchial cryobiopsy (TBCB) sampling in the early stages of…
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Keywords:
diagnosis;
transbronchial cryobiopsy;
langerhans cell;
cell histiocytosis ... See more keywords
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Published in 2017 at "Pathology International"
DOI: 10.1111/pin.12597
Abstract: A pulmonary Langerhans cell histiocytosis is presented in a 40 year‐old woman two years after bilateral lung transplantation for emphysema without any signs of Langerhans cells proliferation in the explanted lungs. A microsatellite molecular analysis…
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Keywords:
langerhans cell;
lung transplantation;
cell histiocytosis;
transplantation ... See more keywords
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Published in 2017 at "Thorax"
DOI: 10.1136/thoraxjnl-2017-210125
Abstract: Pulmonary Langerhans cell histiocytosis (PLCH) is a diffuse lung disease that usually affects young adult smokers. PLCH affects different lung compartments; bronchiolar, interstitial and pulmonary vascular dysfunction may coexist to varying extents, resulting in diverse…
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Keywords:
langerhans cell;
plch;
disease;
cell histiocytosis ... See more keywords
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Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.132048
Abstract: Pulmonary Langerhans cell histiocytosis (PLCH) is a rare, smoking-related, lung disease characterized by dendritic cell (DC) accumulation, bronchiolocentric nodule formation, and cystic lung remodeling. Approximately 50% of PLCH patients harbor somatic BRAF-V600E mutations in cells…
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Keywords:
langerhans cell;
braf v600e;
braf;
pathogenesis ... See more keywords
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Published in 2017 at "European Respiratory Review"
DOI: 10.1183/16000617.0042-2017
Abstract: Lymphangioleiomyomatosis (LAM) and pulmonary Langerhans cell histiocytosis (PLCH) are rare diseases that lead to progressive cystic destruction of the lungs. Despite their distinctive characteristics, these diseases share several features. Patients affected by LAM or PLCH…
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Keywords:
langerhans cell;
insights lymphangioleiomyomatosis;
cell histiocytosis;
pulmonary langerhans ... See more keywords
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Published in 2020 at "Breathe"
DOI: 10.1183/20734735.0003-2020
Abstract: Paediatric pulmonary Langerhans cell histiocytosis (pPLCH) is a rare diffuse cystic lung disease. Unlike pulmonary Langerhans cell histiocytosis (LCH) in adults, which is often seen as an isolated condition with smoking being a major risk…
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Keywords:
langerhans cell;
disease;
paediatric pulmonary;
cell histiocytosis ... See more keywords
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Published in 2021 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v9.i35.11029
Abstract: BACKGROUND Pulmonary Langerhans cell histiocytosis (PLCH) is a relatively rare type of lung disease, common in middle-aged smoking men. It is characterized by proliferation and infiltration of Langerhans cells, and the formation of multiple parabronchial…
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Keywords:
cell histiocytosis;
diagnosis;
langerhans cell;
plch ... See more keywords
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Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12040937
Abstract: Background: Fibrosis in pulmonary Langerhans cell histiocytosis (PLCH) histologically comprises a central scar with septal strands and associated airspace enlargement that produce an octopus-like appearance. The purpose of this study was to identify the octopus…
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Keywords:
langerhans cell;
octopus sign;
cell histiocytosis;
sign ... See more keywords
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Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12061394
Abstract: Pulmonary Langerhans cell histiocytosis (PLCH) is an uncommon diffuse cystic lung disease that occurs almost exclusively in young adult smokers. High-resolution computed tomography of the chest allows a confident diagnosis of PLCH in typical presentation,…
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Keywords:
langerhans cell;
bronchoalveolar lavage;
cell histiocytosis;
pulmonary langerhans ... See more keywords
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Published in 2018 at "Chinese Medical Journal"
DOI: 10.4103/0366-6999.237400
Abstract: Background: Pulmonary Langerhans cell histiocytosis (PLCH) is an interstitial primary pulmonary disease, characterized by Langerhans cell proliferation. It is easily misdiagnosed in children. This study aimed to characterize the clinical manifestations and features of PLCH…
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Keywords:
langerhans cell;
plch children;
organ involvement;
plch ... See more keywords