Exploration of immunotherapy in advanced pulmonary lymphoepithelioma‐like carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34426
Abstract: Pulmonary lymphoepithelioma‐like carcinoma (PLELC) is a rare and histologically distinctive subtype of nonsmall cell lung cancer (NSCLC). High expression of programmed death ligand 1 (PD‐L1) and scarcity of druggable driver mutations raise the potential of… read more here.
Keywords: immunotherapy advanced; pulmonary lymphoepithelioma; immunotherapy; like carcinoma ... See more keywords
Molecular characteristics of primary pulmonary lymphoepithelioma-like carcinoma based on integrated genomic analyses
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00382-6
Abstract: Primary pulmonary lymphoepithelioma-like carcinoma (pLELC) is a rare non-small cell lung cancer (NSCLC) subtype. Clinical features have been described in our previous report, but molecular characteristics remain unclear. Herein, pLELC genomic features were explored. Among… read more here.
Keywords: plelc; carcinoma; primary pulmonary; like carcinoma ... See more keywords
Primary pulmonary lymphoepithelioma-like carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000024987
Abstract: Abstract Rationale: Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare subtype of non-small cell lung cancer (NSCLC). It is predominantly reported in East Asia and currently there is no standard treatment for this disease. We… read more here.
Keywords: lymphoepithelioma like; like carcinoma; primary pulmonary; pulmonary lymphoepithelioma ... See more keywords
Prognostic Value and Clinical Impact of Pretreatment FDG PET in Pulmonary Lymphoepithelioma-Like Carcinoma
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DOI: 10.1097/rlu.0000000000002371
Abstract: Purpose Compared with other forms of non–small cell lung cancer, pulmonary lymphoepithelioma-like carcinoma (LELC) is rarer and portends better outcomes. We sought to investigate the prognostic role and clinical impact of pretreatment 18F-FDG PET in… read more here.
Keywords: pulmonary lymphoepithelioma; impact; 18f fdg; fdg pet ... See more keywords
A Clinical Analysis and Literature Review of Six Cases with Primary Pulmonary Lymphoepithelioma-Like Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/1086697
Abstract: Methods The clinical data of six patients with primary pulmonary lymphoepithelioma-like carcinoma treated in Zhejiang Taizhou Hospital of Taizhou Enze Medical Center (Group) from May 2014 to December 2018 were summarized and analyzed. Combined with… read more here.
Keywords: like carcinoma; pulmonary lymphoepithelioma; lymphoepithelioma like; primary pulmonary ... See more keywords
Case report: mutation analysis of primary pulmonary lymphoepithelioma-like carcinoma via whole-exome sequencing
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic Pathology"
DOI: 10.1186/s13000-019-0811-7
Abstract: BackgroundPrimary pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare tumor subtype accounting for around 0.9% of lung cancers. At present, research on LELC mainly focuses on pathological diagnosis, while the molecular mutation landscape is still unclear.Case… read more here.
Keywords: primary pulmonary; like carcinoma; case; lymphoepithelioma like ... See more keywords
Pulmonary Lymphoepithelioma-Like Carcinoma: A Mini-Review
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DOI: 10.2147/ott.s241337
Abstract: Abstract Pulmonary lymphoepithelioma-like carcinoma (PLELC) is a rare and distinct subtype of non-small-cell lung carcinoma associated with Epstein–Barr virus (EBV) infection. We systematically reviewed the recent research that expands our knowledge about PLELC, with main… read more here.
Keywords: pulmonary lymphoepithelioma; carcinoma; lymphoepithelioma like; 18f fdg ... See more keywords
PD-1/PD-L1 combined with LAG3 is associated with clinical activity of immune checkpoint inhibitors in metastatic primary pulmonary lymphoepithelioma-like carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.951817
Abstract: Primary pulmonary lymphoepithelioma-like carcinoma (PLELC) is an Epstein–Barr virus (EBV)-related, rare subtype of non-small-cell lung cancer (NSCLC). Immune checkpoint inhibitors (ICI) show durable responses in advanced NSCLC. However, their effects and predictive biomarkers in PLELC… read more here.
Keywords: pulmonary lymphoepithelioma; primary pulmonary; immune checkpoint; like carcinoma ... See more keywords
Comparison of Immunotherapy, Chemotherapy, and Chemoimmunotherapy in Advanced Pulmonary Lymphoepithelioma-Like Carcinoma： A Retrospective Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.820302
Abstract: Pulmonary lymphoepithelioma-like carcinoma (pLELC) is a rare subtype of lung cancer that is associated with the Epstein-Barr virus in Asia. Due to the lack of prospective studies, the best first-line treatment and survival outcomes remain… read more here.
Keywords: pulmonary lymphoepithelioma; immunotherapy; chemoimmunotherapy; group ... See more keywords