Interaction of Nel-like molecule 1 with apoptosis related protein 3 with its influence on human dental pulp cells proliferation and differentiation into odontoblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.08.042
Abstract: Nel-like molecule 1 (Nell-1) is an essential positive regulator of tooth development and odontoblast differentiation. However, its precise mechanism remains undetermined. This study aims to explore the possible receptor or binding protein of Nell-1. Results… read more here.
Keywords: human dental; nel like; differentiation; pulp cells ... See more keywords
Biological properties of modified bioactive glass on dental pulp cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dentistry"
DOI: 10.1016/j.jdent.2019.01.017
Abstract: Dental caries is a bacteria-caused condition classified among the most common chronic diseases worldwide. Treatment of dental caries implies the use of materials having regenerative and anti-bacterial properties, and controlling inflammation is critical for successful… read more here.
Keywords: bioactive glass; dpcs; pulp cells; dental pulp ... See more keywords
Transforming growth factor beta 1 increases collagen content, and stimulates procollagen I and tissue inhibitor of metalloproteinase-1 production of dental pulp cells: Role of MEK/ERK and activin receptor-like kinase-5/Smad signaling.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2016.07.014
Abstract: BACKGROUND/PURPOSE In order to clarify the role of transforming growth factor beta 1 (TGF-β1) in pulp repair/regeneration responses, we investigated the differential signaling pathways responsible for the effects of TGF-β1 on collagen turnover, matrix metalloproteinase-3… read more here.
Keywords: collagen content; production; kinase; pulp cells ... See more keywords
TGF-β1 stimulates cyclooxygenase-2 expression and PGE2 production of human dental pulp cells: Role of ALK5/Smad2 and MEK/ERK signal transduction pathways.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2017.07.008
Abstract: BACKGROUND/PURPOSES TGF-β1 is an important growth factor that may influence the odontoblast differentiation and matrix deposition in the reactionary/reparative dentinogenesis to dental caries or other tooth injuries. TGF-β1 exerts its effects through various signaling pathways,… read more here.
Keywords: tgf; pulp cells; dental pulp; pge2 production ... See more keywords
Astrocyte elevated gene‐1 participates in the production of pro‐inflammatory cytokines in dental pulp cells via NF‐&kgr;B signalling pathway
Sign Up to like & getrecommendations! Published in 2018 at "International Endodontic Journal"
DOI: 10.1111/iej.12921
Abstract: AIM To identify the role of astrocyte elevated gene-1 (AEG-1) and the mechanism underlying the inflammatory response in dental pulp cells. METHODOLOGY Astrocyte elevated gene-1 expression was detected at different stages of pulpitis in a… read more here.
Keywords: elevated gene; astrocyte elevated; pulp cells; dental pulp ... See more keywords
Human three-dimensional dental pulp organoids model for toxicity screening of dental materials on dental pulp cells and tissue.
Sign Up to like & getrecommendations! Published in 2021 at "International endodontic journal"
DOI: 10.1111/iej.13641
Abstract: AIM To establish a 3D model for screening biocompatibility of dental materials/drugs on dental pulp cells and tissue. METHODOLOGY Human dental pulp cells (hDPC) and endothelial cells (EC) were mixed with or without human dental… read more here.
Keywords: toxicity screening; model; pulp cells; dental pulp ... See more keywords
Dental properties, ultrastructure, and pulp cells associated with a novel DSPP mutation.
Sign Up to like & getrecommendations! Published in 2018 at "Oral diseases"
DOI: 10.1111/odi.12801
Abstract: OBJECTIVE To investigate physical characteristics and behaviours of dental pulp cells of teeth isolated from a dentinogenesis imperfecta (DGI) patient with a novel dentin sialophosphoprotein (DSPP) mutation. SUBJECTS AND METHODS Whole exome and Sanger sequencing… read more here.
Keywords: dspp mutation; pulp cells; pulp; dentin ... See more keywords
Expansion of Human Dental Pulp Cells In Vitro Under Different Cryopreservation Conditions
Sign Up to like & getrecommendations! Published in 2020 at "In Vivo"
DOI: 10.21873/invivo.12049
Abstract: Background/Aim: To optimize the expansion of human dental pulp cells in vitro by exploring several cryopreservation methodologies. Materials and Methods: The intra-dental pulp tissues from healthy subjects were extracted and divided into three separate tissue… read more here.
Keywords: group; human dental; pulp cells; dental pulp ... See more keywords
Atlas of human dental pulp cells at multiple spatial and temporal levels based on single-cell sequencing analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.993478
Abstract: The dental pulp plays a crucial role in the long-term maintenance of tooth function. The progress of endodontic treatment and pulp tissue regeneration engineering has made pulp-regeneration therapy promising in clinical practice. However, the mechanisms… read more here.
Keywords: dental pulp; pulp cells; single cell; pulp ... See more keywords
piggyBac Transposon-Based Immortalization of Human Deciduous Tooth Dental Pulp Cells with Multipotency and Non-Tumorigenic Potential
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20194904
Abstract: We aimed to immortalize primarily isolated human deciduous tooth-derived dental pulp cells (HDDPCs) by transfection with piggyBac (PB)-based transposon vectors carrying E7 from human papilloma virus 16 or complementary DNA (cDNA) encoding human telomerase reverse… read more here.
Keywords: human deciduous; expression; pulp cells; dental pulp ... See more keywords
Silicate bioceramics elicit proliferation and odonto-genic differentiation of human dental pulp cells.
Sign Up to like & getrecommendations! Published in 2021 at "Dental materials journal"
DOI: 10.4012/dmj.2021-042
Abstract: This study aimed to investigate the effects of silicates on the proliferation and odontogenic differentiation of human dental pulp cells (hDPCs) in vitro. HDPCs were cultured in the presence of calcium silicate (CS) extracts, while… read more here.
Keywords: differentiation human; proliferation; human dental; pulp cells ... See more keywords