Robust expression of SIRT6 inhibits pulpitis via activation of the TRPV1 channel
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3528
Abstract: Invasion of dentinal tubules and pulp tissue by pathogenic bacteria may cause infection leading to pulpitis. Sirtuin 6 (SIRT6) is a NAD‐dependent protein deacetylase encoded by the SIRT6 gene. The effect of SIRT6 on lipopolysaccharide… read more here.
Keywords: pulpitis; sirt6; trpv1 channel; pulp ... See more keywords
Bacterial invasion of pulp blood vessels in teeth with symptomatic irreversible pulpitis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of endodontics"
DOI: 10.1016/j.joen.2021.09.010
Abstract: INTRODUCTION This study described the degenerative changes and infection patterns of the pulp tissue associated with symptomatic irreversible pulpitis. METHODS The material consisted of 32 extracted teeth with untreated deep caries that were clinically and… read more here.
Keywords: pulp; irreversible pulpitis; symptomatic irreversible; pulpitis ... See more keywords
Investigating acute management of irreversible pulpitis: a survey of general dental practitioners in North East England
Sign Up to like & getrecommendations! Published in 2020 at "British Dental Journal"
DOI: 10.1038/s41415-020-1419-8
Abstract: Objective To investigate current strategies of acute management of irreversible pulpitis by general dental practitioners. Design A postal survey was sent to a representative sample based on postal code to 180 dentists registered with the… read more here.
Keywords: general dental; irreversible pulpitis; acute management; management irreversible ... See more keywords
Pulpotomy for teeth with irreversible pulpitis in immature permanent teeth: a retrospective case series study
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-56975-6
Abstract: To evaluate the success of pulpotomy in treating immature permanent teeth with irreversible pulpitis. This case series included patients with irreversible pulpitis admitted to the Department of Oral Medicine at the author’s Hospital between 2015… read more here.
Keywords: irreversible pulpitis; pulpotomy; teeth irreversible; immature permanent ... See more keywords
Combination of resolvin E1 and lipoxin A4 promotes the resolution of pulpitis by inhibiting NF-κB activation through upregulating sirtuin 7 in dental pulp fibroblasts.
Sign Up to like & getrecommendations! Published in 2022 at "Cell proliferation"
DOI: 10.1111/cpr.13227
Abstract: OBJECTIVES To determine whether the combination of resolvin E1 (RvE1) and lipoxin A4 (LXA4) could promote resolution of pulpitis and to investigate the mechanism. MATERIALS AND METHODS Preliminary screening was first conducted in four specialized… read more here.
Keywords: expression; activation; combination; pulpitis ... See more keywords
Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study
Sign Up to like & getrecommendations! Published in 2017 at "International Endodontic Journal"
DOI: 10.1111/iej.12614
Abstract: AIM To prospectively investigate the clinical and radiographic success rates of pulpotomy in permanent molars with clinical signs and symptoms suggestive of irreversible pulpitis using mineral trioxide aggregate (MTA) as a pulp dressing agent. METHODOLOGY… read more here.
Keywords: permanent molars; irreversible pulpitis; pulpotomy permanent; molars clinical ... See more keywords
Exosomes derived from stem cells from the apical papilla alleviate inflammation in rat pulpitis by upregulating regulatory T cells.
Sign Up to like & getrecommendations! Published in 2022 at "International endodontic journal"
DOI: 10.1111/iej.13721
Abstract: AIM To evaluate the effects of exosomes derived from stem cells from the apical papilla (SCAP-Exos) in rats with experimentally induced pulpitis and the effects of SCAP-Exos on the conversion of regulatory T cells (Tregs)… read more here.
Keywords: derived stem; inflammation; scap exos; pulpitis ... See more keywords
Regulation of caries‐induced pulp inflammation by NLRP3 inflammasome: A laboratory‐based investigation
Sign Up to like & getrecommendations! Published in 2022 at "International Endodontic Journal"
DOI: 10.1111/iej.13855
Abstract: Abstract Aim To evaluate the expression and function of the nod‐like receptor pyrin domain containing 3 (NLRP3) inflammasome in caries induced pulpitis. Methodology NLRP3 expression was determined with immunohistochemistry in the dental pulp and qPCR… read more here.
Keywords: inhibitor; caries induced; treatment; pulpitis ... See more keywords
Teeth with vital pulps and stage III periodontitis unresponsive to therapy exhibit a pulpal inflammatory profile similar to symptomatic irreversible pulpitis.
Sign Up to like & getrecommendations! Published in 2024 at "International endodontic journal"
DOI: 10.1111/iej.14139
Abstract: AIM The aim of this study is to investigate the expression of inflammatory biomarkers (TNF-α, IL-10, IL-1β) and the pulpitis-associated miRNA (miR-30a-5p and miR-128-3p) in pulp tissue samples from unrestored teeth with a vital normal… read more here.
Keywords: mir 30a; inflammatory; pulp; expression ... See more keywords
Comparative analysis of deep dentinal caries microbiota in teeth with normal pulp, reversible pulpitis, symptomatic and asymptomatic irreversible pulpitis.
Sign Up to like & getrecommendations! Published in 2025 at "International endodontic journal"
DOI: 10.1111/iej.14221
Abstract: AIM To characterize the deep dentinal caries microbiota in teeth diagnosed with normal pulp with deep caries (NP), reversible pulpitis (RP), symptomatic irreversible pulpitis (SIP), and asymptomatic irreversible pulpitis (AIP), and to identify potential key… read more here.
Keywords: dentinal caries; irreversible pulpitis; analysis; deep dentinal ... See more keywords
Symptom correlation and spatial distribution of inflammatory mediators in pulpitis—A preliminary study
Sign Up to like & getrecommendations! Published in 2025 at "International Endodontic Journal"
DOI: 10.1111/iej.14275
Abstract: Abstract Aim To evaluate the association of inflammatory mediators with clinical signs and symptoms and their spatial distribution in teeth with pulpitis. Methodology Fifty permanent teeth from adults with clinical diagnoses of normal pulp (n = 17),… read more here.
Keywords: irreversible pulpitis; spatial distribution; inflammatory mediators; blood ... See more keywords