Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway
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DOI: 10.1038/s41417-019-0098-6
Abstract: Cabozantinib is a multi-kinase inhibitor targeting MET, AXL, and VEGFR2, and has been approved for use in multiple malignancies. The means by which Cabozantinib acts to target colorectal cancer (CRC) cells remains poorly understood, and… read more here.
Keywords: crc cells; apoptosis; puma dependent; signaling pathway ... See more keywords