Expressions of p53 and PUMA in fibroblasts of systemic sclerosis patients are normal at transcription level
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DOI: 10.1111/jocd.12420
Abstract: Systemic sclerosis (SSc) fibroblasts show resistance apoptosis mechanisms, which enhances the fibrosis stage of the disease. Impaired function of p53 upregulated modulator of apoptosis (PUMA) has been related to deficits in p53‐dependant apoptosis pathway. This… read more here.
Keywords: puma fibroblasts; expressions p53; p53 puma; fibroblasts systemic ... See more keywords