Analysis of Inflammasome Activation in Response to Yersinia Infection by Fluorescence Microscopy Detection of Active Caspase-1 Puncta.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9541-7_16
Abstract: The type of cell death triggered by a particular environmental stimulus influences the outcome of infection or inflammatory disease processes. The ability to identify the cell death pathway that is activated in response to infection… read more here.
Keywords: caspase; microscopy; puncta; infection ... See more keywords
The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.10.017
Abstract: The role of agrin, Lrp4 and MuSK, key organizers of neuromuscular synaptogenesis, in the developing CNS is only poorly understood. We investigated the role of these proteins in cultured mouse embryonic cortical neurons from wildtype… read more here.
Keywords: synaptogenesis; puncta; lrp4 musk; agrin lrp4 ... See more keywords
Reversible acetylation modulates dishevelled-2 puncta formation in canonical Wnt signaling activation
Sign Up to like & getrecommendations! Published in 2020 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00229-0
Abstract: Dear Editor, Dishevelled-2 (DVL2) is a central adaptor protein that propagates signals from upstream receptors to downstream effector β-catenin in canonical Wnt signaling. At high local concentration, DVL2 assembles into signalosomes through DIX domain-mediated homo-polymerization… read more here.
Keywords: acetylation; puncta; supplementary fig; formation ... See more keywords
Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-17-0901
Abstract: Chemotherapy-induced autophagy is a proposed mechanism of chemoresistance and potential therapeutic target in osteosarcoma. We evaluated heat shock protein 27 (HSP27) and autophagy-related proteins as predictors of pathologic treatment response and prognostic markers among osteosarcoma… read more here.
Keywords: chemotherapy; puncta; treatment; lc3b puncta ... See more keywords
Diagnosis of lacrimal punctum lesions using optical coherence tomography: a preliminary study.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2020.06.07
Abstract: AIM To study the imaging characteristics of lacrimal punctum lesion with optical coherence tomography (OCT), and provide imaging basis for the diagnosis and treatment of lacrimal punctum diseases. METHODS A total of 25 patients (28… read more here.
Keywords: punctum; optical coherence; diagnosis; puncta ... See more keywords
Preliminary report on screening IGSF3 gene mutation in families with congenital absence of lacrimal puncta and canaliculi.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2020.09.02
Abstract: AIM To investigate the variation of IGSF3 gene in three families with congenital absence of lacrimal puncta and canaliculi, and to lay a foundation for further research on the pathogenic gene of congenital lacrimal duct… read more here.
Keywords: lacrimal puncta; absence lacrimal; puncta canaliculi; puncta ... See more keywords
SynapseJ: An Automated, Synapse Identification Macro for ImageJ
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2021.731333
Abstract: While electron microscopy represents the gold standard for detection of synapses, a number of limitations prevent its broad applicability. A key method for detecting synapses is immunostaining for markers of pre- and post-synaptic proteins, which… read more here.
Keywords: microscopy; puncta; analysis; imagej ... See more keywords
Endoplasmic reticulum tubules limit the size of misfolded protein condensates
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.71642
Abstract: The endoplasmic reticulum (ER) is composed of sheets and tubules. Here we report that the COPII coat subunit, SEC24C, works with the long form of the tubular ER-phagy receptor, RTN3, to target dominant-interfering mutant proinsulin… read more here.
Keywords: endoplasmic reticulum; reticulum tubules; puncta; akita puncta ... See more keywords