Stereoselective Synthesis of Optically Pure 2-Amino-2'-hydroxy-1,1'-binaphthyls.
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DOI: 10.1021/acs.orglett.8b00800
Abstract: Direct entry to optically pure 2-amino-2'-hydroxy-1,1'-binaphthyl (NOBIN) derivatives by an iron-catalyzed stereoselective oxidative cross-coupling reaction between 2-naphthol and 2-aminonaphthalene with a labile chiral auxiliary is reported. This efficient method offers entry to tailor-designed ( R… read more here.
Keywords: optically pure; pure amino; stereoselective synthesis; amino hydroxy ... See more keywords