Purging Exhausted Virus-Specific CD8 T Cell Phenotypes by Somatic Cell Reprogramming
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DOI: 10.1089/aid.2017.0161
Abstract: Abstract Cytotoxic T cells are critical in controlling virus infections. However, continuous antigen stimulation and negative regulatory factors cause CD8 T cells to enter a dysfunctional state (T cell exhaustion), resulting in viral persistence. We… read more here.
Keywords: purging exhausted; somatic cell; cell reprogramming; exhausted virus ... See more keywords