Comparison of purification strategies for antibodies used in a broad spectrum host cell protein immunoassay
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DOI: 10.1002/bit.26482
Abstract: Host cell proteins (HCPs) are a heterogeneous mixture of impurities that should be minimized in bulk preparations of biotechnologically produced medicines. Immunoassays are commonly used to detect and measure HCPs in therapeutic products, and a… read more here.
Keywords: host cell; purification; comparison purification; purification strategies ... See more keywords
Protein purification strategies must consider downstream applications and individual biological characteristics
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Cell Factories"
DOI: 10.1186/s12934-022-01778-5
Abstract: Background Proteins are used as reagents in a broad range of scientific fields. The reliability and reproducibility of experimental data will largely depend on the quality of the (recombinant) proteins and, consequently, these should undergo… read more here.
Keywords: downstream applications; purification strategies; characteristics protein; protein purification ... See more keywords