Articles with "purified prions" as a keyword



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Conformational diversity in purified prions produced in vitro

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Published in 2023 at "PLOS Pathogens"

DOI: 10.1371/journal.ppat.1011083

Abstract: Prion diseases are caused by misfolding of either wild-type or mutant forms of the prion protein (PrP) into self-propagating, pathogenic conformers, collectively termed PrPSc. Both wild-type and mutant PrPSc molecules exhibit conformational diversity in vivo,… read more here.

Keywords: prpsc; conformational diversity; diversity; purified prions ... See more keywords