Sign Up to like & get
recommendations!
0
Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.06.017
Abstract: Sustained activation of STAT3 is closely related to the cancer development, but the inhibitors for STAT3 overexpression are still in the clinical research stage. In this study, a series of 2,6-disubstituted purine derivatives were designed…
read more here.
Keywords:
disubstituted purine;
purine derivatives;
small molecule;
molecule inhibitors ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2021 at "Czech Journal of Food Sciences"
DOI: 10.17221/297/2020-cjfs
Abstract: In this study, simultaneous quantification of allantoin, uric acid, xanthine, and hypoxanthine in cow milk by solid phase extraction (SPE) and high performance liquid chromatography-diode array detection (HPLC-DAD) method was perform. Five different SPE cartridges…
read more here.
Keywords:
purine derivatives;
hplc dad;
cow milk;
spe ... See more keywords
Sign Up to like & get
recommendations!
2
Published in 2023 at "Journal of dairy science"
DOI: 10.3168/jds.2023-23275
Abstract: The objective of this study was to assess the growth, apparent total-tract digestibility of nutrients, the prevalence of coccidia, and purine derivatives (PD) in post-weaned heifers when limit-fed a diet supplemented with sodium butyrate (SB).…
read more here.
Keywords:
apparent total;
growth;
total tract;
limit fed ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Materials"
DOI: 10.3390/ma15207376
Abstract: Caffeine and theophylline are compounds with important applications in the pharmaceutical industry and other fields of the chemical industry. These purine derivatives have simple chemical structures, therefore, the evaluation of their sublimation process contributes to…
read more here.
Keywords:
mass transfer;
sublimation;
transfer coefficients;
purine derivatives ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14061294
Abstract: We report 31 new compounds designed, synthesized and evaluated on Bcr-Abl, BTK and FLT3-ITD as part of our program to develop 2,6,9-trisubstituted purine derivatives as inhibitors of oncogenic kinases. The design was inspired by the…
read more here.
Keywords:
abl btk;
bcr abl;
purine derivatives;
btk flt3 ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2019 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2018-0291
Abstract: AIM Identification of new antiproliferative compounds. METHODOLOGY Four series of compounds were synthesized by the Mitsunobu reaction. Their antiproliferative activity was studied against several cancer cells and a noncancerous fibroblast cell line. Their apoptotic activity…
read more here.
Keywords:
purine derivatives;
derivatives heterocyclic;
moieties related;
heterocyclic moieties ... See more keywords