Articles with "purine pteridine" as a keyword



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Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAFV600E

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Published in 2023 at "Pharmaceuticals"

DOI: 10.3390/ph16050716

Abstract: The investigation of novel EGFR and BRAFV600E dual inhibitors is intended to serve as targeted cancer treatment. Two sets of purine/pteridine-based derivatives were designed and synthesized as EGFR/BRAFV600E dual inhibitors. The majority of the compounds… read more here.

Keywords: dual inhibitors; based derivatives; pteridine based; egfr brafv600e ... See more keywords