Stability of the chlorinated derivatives of the DNA/RNA nucleobases, purine and pyrimidine toward radical formation via homolytic CCl bond dissociation
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Quantum Chemistry"
DOI: 10.1002/qua.25319
Abstract: The chlorinated derivatives of nucleobases (and nucleosides), as well as those of purine, have well-established anticancer activity, and in some cases, are also shown to be involved in the link between chronic inflammatory conditions and… read more here.
Keywords: ccl bond; ccl; homolytic ccl; nucleobases purine ... See more keywords
Electrochemical determination of purine and pyrimidine bases using copper doped cerium oxide nanoparticles.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2018.06.046
Abstract: Deoxyribonucleic acid (DNA), a primary unit of heredity in all types of organisms, consists of purine and pyrimidine bases in such a way that the amount of guanine (GU) is equal to cytosine (CY) and… read more here.
Keywords: determination purine; pyrimidine bases; purine pyrimidine;
Using an In-Sample Addition of Medronic Acid for the Analysis of Purine- and Pyrimidine-Related Derivatives and Its Application in the Study of Lung Adenocarcinoma A549 Cell Lines by LC-MS/MS.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00736
Abstract: Intracellular purine- and pyrimidine-related derivatives are vital molecules for preserving genetic information and are essential for cellular bioenergetics and signal transduction. This study developed a practical liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantifying intracellular… read more here.
Keywords: related derivatives; medronic acid; pyrimidine related; purine pyrimidine ... See more keywords
AB0216 THE IMBALANCE OF ACTIVITIES OF PURINE AND PYRIMIDINE METABOLISM ENZYMES IN RED BLOOD CELLS OF SYSTEMIC SCLERODERMA PATIENTS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.2125
Abstract: Background The systemic scleroderma (SSc) is connective tissue disease of unknown cause. The key points in development of SSc are the increased number of high collagen-producing fibroblasts in the skin, endothelial dysfunction and immune activation.… read more here.
Keywords: red blood; blood cells; activity; pyrimidine metabolism ... See more keywords