Treatment of chronic neuropathic pain: purine receptor modulation.
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DOI: 10.1097/j.pain.0000000000001857
Abstract: Extracellular nucleosides and nucleotides have widespread functions in responding to physiological stress. The "purinome" encompasses four G protein-coupled receptors (GPCRs) for adenosine, eight GPCRs activated by nucleotides (P2YRs), seven adenosine 5'-triphosphate(ATP)-gated P2X ion channels, as… read more here.
Keywords: chronic neuropathic; receptor modulation; neuropathic pain; purine receptor ... See more keywords