Articles with "purine scaffold" as a keyword



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Effects of purine-scaffold inhibitors on HUVECs: Involvement of the purinergic pathway and interference with ATP. Implications for preventing the adverse effects of extracellular Grp94

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Published in 2019 at "Biochemistry and Biophysics Reports"

DOI: 10.1016/j.bbrep.2019.100661

Abstract: Background Extracellular Glucose-regulated protein94 (Grp94) is linked to pathological conditions disrupting the obligatory intracellular location of this Heat Shock Protein (HSP). In plasma, Grp94 is linked to IgG in complexes that drive adverse effects on… read more here.

Keywords: grp94 igg; purine scaffold; scaffold inhibitors; grp94 ... See more keywords