Effects of purine-scaffold inhibitors on HUVECs: Involvement of the purinergic pathway and interference with ATP. Implications for preventing the adverse effects of extracellular Grp94
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2019.100661
Abstract: Background Extracellular Glucose-regulated protein94 (Grp94) is linked to pathological conditions disrupting the obligatory intracellular location of this Heat Shock Protein (HSP). In plasma, Grp94 is linked to IgG in complexes that drive adverse effects on… read more here.
Keywords: grp94 igg; purine scaffold; scaffold inhibitors; grp94 ... See more keywords
Purine Scaffold in Agents for Cancer Treatment
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DOI: 10.1021/acsomega.5c00340
Abstract: Cancer represents one of the most important and often fatal threats in the human population. Regarding the natural products, the purine scaffold appears in the purine bases in nucleic acids. Purine and its natural derivatives… read more here.
Keywords: purine scaffold; cancer; agents cancer; cancer treatment ... See more keywords