Purinergic Signaling in Glioma Progression.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-30651-9_5
Abstract: Among the pathological alterations that give tumor cells invasive potential, purinergic signaling is emerging as an important component. Studies performed in in vitro, in vivo and ex vivo glioma models indicate that alterations in the purinergic signaling… read more here.
Keywords: glioma progression; purinergic; purinergic signaling; tumor ... See more keywords
Characterization of macrophage phenotype, redox, and purinergic response upon chronic treatment with methionine and methionine sulfoxide in mice
Sign Up to like & getrecommendations! Published in 2020 at "Amino Acids"
DOI: 10.1007/s00726-020-02841-4
Abstract: Hypermethioninemia is a disorder characterized by high plasma levels of methionine (Met) and its metabolites such as methionine sulfoxide (MetO). Studies have reported associated inflammatory complications, but the mechanisms involved in the pathophysiology of hypermethioninemia… read more here.
Keywords: purinergic; methionine; upon chronic; met meto ... See more keywords
Optical control of purinergic signaling
Sign Up to like & getrecommendations! Published in 2021 at "Purinergic Signalling"
DOI: 10.1007/s11302-021-09799-2
Abstract: Purinergic signaling plays a pivotal role in physiological processes and pathological conditions. Over the past decades, conventional pharmacological, biochemical, and molecular biology techniques have been utilized to investigate purinergic signaling cascades. However, none of them… read more here.
Keywords: purinergic; control purinergic; biology; optical control ... See more keywords
Nanobodies as probes to investigate purinergic signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114394
Abstract: Nanobodies (VHHs) are the single variable immunoglobulin domains of heavy chain antibodies (hcAbs) that naturally occur in alpacas and other camelids. The two variable domains of conventional antibodies typically interact via a hydrophobic interface. In… read more here.
Keywords: nanobodies probes; purinergic; investigate purinergic; pharmacology ... See more keywords
Astrocytic purinergic signaling contributes to the development and maintenance of neuropathic pain via modulation of glutamate release.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurochemistry"
DOI: 10.1111/jnc.15800
Abstract: Although activation of astrocytes is critical in developing neuropathic pain (NP) following nerve injury, the underlying mechanisms of NP and therapeutic management for NP are still vague. Importantly, the decreases in the levels of astrocytic… read more here.
Keywords: glutamate; purinergic; glutamate release; neuropathic pain ... See more keywords
Purinergic signaling is enhanced in the absence of UT‐A1 and UT‐A3
Sign Up to like & getrecommendations! Published in 2021 at "Physiological Reports"
DOI: 10.14814/phy2.14636
Abstract: ATP is an important paracrine regulator of renal tubular water and urea transport. The activity of P2Y2, the predominant P2Y receptor of the medullary collecting duct, is mediated by ATP, and modulates urinary concentration. To… read more here.
Keywords: purinergic; transport; signaling enhanced; enhanced absence ... See more keywords
Pharmacological Profile of the Purinergic P2Y Receptors That Modulate, in Response to ADPβS, the Vasodepressor Sensory CGRPergic Outflow in Pithed Rats
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16030475
Abstract: Calcitonin gene-related peptide (CGRP), an endogenous neuropeptide released from perivascular sensory nerves, exerts a powerful vasodilatation. Interestingly, adenosine triphosphate (ATP) stimulates the release of CGRP by activation of prejunctional P2X2/3 receptors, and adenosine 5′-O-2-thiodiphosphate (ADPβS),… read more here.
Keywords: sensory cgrpergic; vasodepressor; purinergic; adp min ... See more keywords