Therapeutic Potential of the Purinergic System in Major Depressive Disorder Associated with COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-022-01215-6
Abstract: Neuroinflammation is closely related to the development of depression, since the latter is caused, among other factors, by inflammatory processes, mainly related to the activation of microglia and expression of specific genes, which occurs during… read more here.
Keywords: potential purinergic; system; therapeutic potential; purinergic system ... See more keywords
Purinergic system dysfunctions in subjects with bipolar disorder: A comparative cross-sectional study.
Sign Up to like & getrecommendations! Published in 2017 at "Comprehensive psychiatry"
DOI: 10.1016/j.comppsych.2016.09.011
Abstract: BACKGROUND Subjects with bipolar mania may have increased uric acid levels, based on a purinergic system dysfunction with reduced neurotransmission of adenosine. We investigated whether there were differences in uric acid levels between individuals with… read more here.
Keywords: uric acid; disorder; bipolar disorder; subjects bipolar ... See more keywords
Purinergic system displays an anti-inflammatory profile in serum of silver catfish experimentally infected with Streptococcus agalactiae: An attempt to ameliorate the inflammatory response.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.11.060
Abstract: The purinergic system is recognized to modulate extracellular adenosine triphosphate (ATP) and related nucleotides through the activities of triphosphate diphosphohydrolase (NTPDase), 5'-nucleotidase, and adenosine deaminase (ADA), thereby playing an essential role in the immunoregulation of… read more here.
Keywords: experimentally infected; system; agalactiae; inflammatory ... See more keywords
Aeromonas caviae alters the activities of ecto-enzymes that hydrolyze adenine nucleotides in fish thrombocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.12.044
Abstract: It is recognized that the purinergic system, through the activities of ectonucleoside triphosphate diphosphohydrolase (E-NTPDase), ecto-5'-nucleotidase (E-5'-nucleotidase), and ecto-adenosine deaminase (E-ADA), is involved in the regulation and modulation of the physiological and pathological events linked… read more here.
Keywords: ecto enzymes; fish thrombocytes; activation; aeromonas caviae ... See more keywords
Dysfunction of the Purinergic System in Bipolar Disorder
Sign Up to like & getrecommendations! Published in 2022 at "Neuropsychobiology"
DOI: 10.1159/000520146
Abstract: Objective: To verify the purinergic hypothesis of bipolar disorder (BD), we assessed the concentration of various components of the purinergic system in manic and depressed bipolar patients. Methods: Sixty-two patients (19 male and 43 female),… read more here.
Keywords: purinergic system; system; dysfunction purinergic; male female ... See more keywords