Regioselective C6-H Hydroxyalkylation of Purines and Purine Nucleosides via α-C-H Functionalization of Alcohols at Room Temperature.
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DOI: 10.1021/acs.orglett.2c01680
Abstract: The highly regioselective C6-H hydroxylalkylation of purines and purine nucleosides within 10 min via the α-C(sp3)-H functionalization of alcohols at room temperature is reported here for the first time. The reaction tolerated various functional groups,… read more here.
Keywords: purine nucleosides; purines purine; functionalization alcohols; room temperature ... See more keywords