Long non-coding RNA p53 upregulated regulator of p53 levels (PURPL) promotes the development of gastric cancer
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DOI: 10.1080/21655979.2021.2017588
Abstract: ABSTRACT Gastric cancer (GC), one of the most prevalent malignancies across the world, has an increasing incidence rate. Long non-coding RNA (lncRNA) PURPL (also referred to as LINC01021) has been demonstrated to influence malignant GC… read more here.
Keywords: non coding; purpl; p53; gastric cancer ... See more keywords
Context-Dependent Function of Long Noncoding RNA PURPL in Transcriptome Regulation during p53 Activation
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DOI: 10.1128/mcb.00289-22
Abstract: PURPL is a p53-induced lncRNA that suppresses basal p53 levels. Here, we investigated PURPL upon p53 activation in liver cancer cells, where it is expressed at significantly higher levels than other cell types. ABSTRACT PURPL… read more here.
Keywords: function; p53 activation; upon p53; purpl ... See more keywords