Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies
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DOI: 10.3390/pharmaceutics15020320
Abstract: Antisense and small interfering RNA (siRNA) oligonucleotides have been recognized as powerful therapeutic compounds for targeting mRNAs and inducing their degradation. However, a major obstacle is that unmodified oligonucleotides are not readily taken up into… read more here.
Keywords: purposes simple; peptide oligonucleotide; lipid peptide; conjugates therapeutic ... See more keywords