Conversion of lignin-derived 3-methoxycatechol to the natural product purpurogallin using bacterial P450 GcoAB and laccase CueO.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11738-5
Abstract: Purpurogallin is a natural benzotropolone extracted from Quercus spp, which has antioxidant, anticancer, and anti-inflammatory properties. Purpurogallin is typically synthesized from pyrogallol using enzymatic or metal catalysts, neither economically feasible nor environmentally friendly. 3-Methoxycatechol (3-MC)… read more here.
Keywords: purpurogallin; cueo; laccase cueo; lignin derived ... See more keywords
Insights into the inhibitory mechanism of purpurogallin on xanthine oxidase by multiple spectroscopic techniques and molecular docking
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.129772
Abstract: Abstract Purpurogallin, a benzotropolone containing natural compound found in nutgall and oak bark, was investigated for its inhibitory mechanism on xanthine oxidase (XO) by multispectroscopic methods and molecular docking analysis. The enzyme kinetic analysis showed… read more here.
Keywords: mechanism purpurogallin; xanthine oxidase; inhibitory mechanism; purpurogallin ... See more keywords
A New Family of Jumonji C Domain-Containing KDM Inhibitors Inspired by Natural Product Purpurogallin
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2020.00312
Abstract: Aberrant epigenetic modifications are involved in cancer development. Jumonji C domain-containing histone lysine demethylases (KDMs) are found mainly up-regulated in breast, prostate, and colon cancer. Currently, growing interest is focusing on the identification and development… read more here.
Keywords: domain containing; purpurogallin; natural product; product purpurogallin ... See more keywords
A New Approach for Quantifying Purpurogallin in Brewed Beverages Using LC-MS in Combination with Solid Phase Extraction
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11101429
Abstract: Purpurogallin (PPG) is a phenolic compound known for its high antioxidant properties in plant-based food materials. However, there is no easy and reliable method for direct determination of PPG in brewed beverages owing to its… read more here.
Keywords: brewed beverages; ppg; purpurogallin; phase extraction ... See more keywords