Repetitive Head Impacts and Perivascular Space Volume in Former American Football Players
Sign Up to like & getrecommendations! Published in 2024 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2024.28687
Abstract: IMPORTANCE Exposure to repetitive head impacts (RHI) is associated with increased risk for neurodegeneration. Accumulation of toxic proteins due to impaired brain clearance is suspected to play a role. OBJECTIVE To investigate whether perivascular space… read more here.
Keywords: pvs volume; football; football players; former american ... See more keywords
Glymphatic, Structural, and Cognitive Changes During Breast Cancer Chemotherapy: A Longitudinal MRI Study
Sign Up to like & getrecommendations! Published in 2025 at "Human Brain Mapping"
DOI: 10.1002/hbm.70334
Abstract: The glymphatic system maintains brain homeostasis through cerebrospinal fluid transport and waste clearance. Its potential involvement in chemotherapy‐related cognitive impairment remains largely unexplored due to limited in vivo evidence. In this prospective longitudinal study, 126… read more here.
Keywords: pvs volume; breast cancer; chemotherapy; volume fraction ... See more keywords
Volumetric distribution of perivascular space in relation to mild cognitive impairment
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2020.12.010
Abstract: Vascular contributions to early cognitive decline are increasingly recognized, prompting further investigation into the nature of related changes in perivascular spaces (PVS). Using magnetic resonance imaging, we show that, compared to a cognitively normal sample,… read more here.
Keywords: cognitive impairment; volume fraction; distribution; pvs volume ... See more keywords
Relationship of Perivascular Space Markers With Incident Dementia in Cerebral Small Vessel Disease
Sign Up to like & getrecommendations! Published in 2024 at "Stroke"
DOI: 10.1161/strokeaha.123.045857
Abstract: BACKGROUND: Recent studies, using diffusion tensor image analysis along the perivascular space (DTI-ALPS), suggest impaired perivascular space (PVS) function in cerebral small vessel disease, but they were cross-sectional, making inferences on causality difficult. We determined… read more here.
Keywords: pvs volume; dementia; dti; cerebral small ... See more keywords
Perivascular spaces as a marker of disease severity and neurodegeneration in patients with behavioral variant frontotemporal dementia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.1003522
Abstract: Background Behavioural Variant Frontotemporal Dementia (bvFTD) is a rapidly progressing neurodegenerative proteinopathy. Perivascular spaces (PVS) form a part of the brain’s glymphatic clearance system. When enlarged due to poor glymphatic clearance of toxic proteins, PVS… read more here.
Keywords: change; disease; pvs; pvs volume ... See more keywords