Aberrant expression of long non‐coding RNA PVT1 in allergic rhinitis children: Correlation with disease risk, symptoms, and Th1/Th2 imbalance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24281
Abstract: Long non‐coding RNA plasmacytoma variant translocation 1 (lnc‐PVT1) exacerbates inflammation and induces T helper (Th) 1/Th2 imbalance in allergic diseases, but its clinical role in allergic rhinitis (AR) remains unclear. Hence, we conducted this study… read more here.
Keywords: long non; th2 imbalance; allergic rhinitis; pvt1 ... See more keywords
Analysis of anti‐apoptotic PVT1 oncogene and apoptosis‐related proteins (p53, Bcl2, PD‐1, and PD‐L1) expression in thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24390
Abstract: An aberrant expression of long non‐coding RNA PVT1 has been associated with apoptosis in various cancer types. We aimed to explore the PVT1 and four apoptosis‐related proteins (p53, Bcl2, and PD‐1/PD‐L1) signature in thyroid cancer… read more here.
Keywords: p53 bcl2; related proteins; proteins p53; expression ... See more keywords
Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28264
Abstract: The aim of this study is to investigate the effects of long‐chain noncoding RNA plasmacytoma variant translocation 1 (PVT1) on the activation of astrocytes and the expression of brain‐derived neurotrophic factor (BDNF) in hippocampus tissues… read more here.
Keywords: activation astrocytes; hippocampus; pvt1; expression ... See more keywords
lncRNA PVT1 promotes the migration of gastric cancer by functioning as ceRNA of miR‐30a and regulating Snail
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29881
Abstract: Although the incidence and mortality of gastric cancer (GC) are slowly decreasing, the overall prognosis of GC patients with distal metastasis remains dismal. Long non‐coding RNA PVT1 has been verified to function as a tumor… read more here.
Keywords: gastric cancer; pvt1; metastasis; snail ... See more keywords
Hypermethylation‐mediated downregulation of lncRNA PVT1 promotes granulosa cell apoptosis in premature ovarian insufficiency via interacting with Foxo3a
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30222
Abstract: Long noncoding RNA PVT1 is involved in the progression of female gynecological cancers. However, the role of PVT1 in ovarian granulosa cell apoptosis‐mediated premature ovarian insufficiency (POI) remains unclear. This study aims to elucidate the… read more here.
Keywords: granulosa cell; cell apoptosis; pvt1;
Long noncoding RNA PVT1 accelerates the growth of placental trophoblasts in preeclampsia through the microRNA‐24‐3p/HSD11B2 axis
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DOI: 10.1002/mrd.23575
Abstract: Long noncoding RNA plasmacytoma variant translocation 1 (PVT1) is essential for the maintenance of normal functions of trophoblasts in preeclampsia (PE). This study aims to decipher the concrete mechanism of PVT1 with the microRNA‐24‐3p/Type‐2 11β‐hydroxysteroid… read more here.
Keywords: hsd11b2; htr svneo; growth; pvt1 ... See more keywords
Long non-coding RNA PVT1 interacts with MYC and its downstream molecules to synergistically promote tumorigenesis
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DOI: 10.1007/s00018-019-03222-1
Abstract: Numerous studies have shown that non-coding RNAs play crucial roles in the development and progression of various tumor cells. Plasmacytoma variant translocation 1 (PVT1) mainly encodes a long non-coding RNA (lncRNA) and is located on… read more here.
Keywords: pvt1; long non; non coding; coding rna ... See more keywords
LncPVT1 promotes cartilage degradation in diabetic OA mice by downregulating miR-146a and activating TGF-β/SMAD4 signaling
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DOI: 10.1007/s00774-020-01199-7
Abstract: To investigate the role of LncRNA PVT1 (plasmacytoma variant translocation 1) in hyperglycemia-triggered cartilage damage using the diabetic osteoarthritis (OA) mice model. Streptozotocin (STZ) was used to induce mouse diabetes. Knee OA model was induced… read more here.
Keywords: mir 146a; pvt1; tgf smad4; mice ... See more keywords
LncRNA PVT1 accelerates LPS-induced septic acute kidney injury through targeting miR-17-5p and regulating NF-κB pathway
Sign Up to like & getrecommendations! Published in 2021 at "International Urology and Nephrology"
DOI: 10.1007/s11255-021-02905-8
Abstract: Long noncoding RNA PVT1 is associated with diverse human diseases, including acute kidney injury (AKI). However, our understandings of PVT1 on septic AKI are limited. The septic AKI model was constructed through lipopolysaccharide (LPS) treatment.… read more here.
Keywords: mir; acute kidney; pvt1; kidney injury ... See more keywords
LncRNA PVT1 induces aggressive vasculogenic mimicry formation through activating the STAT3/Slug axis and epithelial-to-mesenchymal transition in gastric cancer
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DOI: 10.1007/s13402-020-00532-6
Abstract: Vasculogenic mimicry (VM), a vessel-like network formed by highly aggressive tumor cells, plays an important role in accelerating cancer progression. This special vascularization pattern is closely associated with a poor prognosis in various cancers. As… read more here.
Keywords: gastric cancer; pvt1; vasculogenic mimicry; formation ... See more keywords
LncRNA-PVT1 activates lung fibroblasts via miR-497-5p and is facilitated by FOXM1.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.112030
Abstract: It is little known about the lncRNA-PVT1 effect on occupational pulmonary fibrosis, although researches show it plays an essential role in cancer. Studies reveal that lung fibroblast activation is one of the key events in… read more here.
Keywords: lncrna pvt1; lung fibroblasts; pvt1; mir 497 ... See more keywords