Minimum effective dose of clemastine in a mouse model of preterm white matter injury
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DOI: 10.1038/s41390-024-03326-w
Abstract: Preterm white matter injury (PWMI) is the most common cause of brain injury in premature neonates. PWMI involves a differentiation arrest of oligodendrocytes, the myelinating cells of the central nervous system. Clemastine was previously shown… read more here.
Keywords: clemastine; pwmi; minimum effective; injury ... See more keywords
NAT10-mediated ac4C modification of Lipin1 mRNA contributes to the pathogenesis of PWMI
Sign Up to like & getrecommendations! Published in 2025 at "JCI Insight"
DOI: 10.1172/jci.insight.193712
Abstract: Preterm white matter injury (PWMI) is a leading cause of cerebral palsy and chronic neurological disabilities in premature infants. It is characterized by defects in oligodendrocyte precursor cell (OPC) differentiation and dysmyelination. Currently, there are… read more here.
Keywords: lipin1; pwmi; lipin1 mrna; ac4c modification ... See more keywords