Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer
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DOI: 10.1002/med.21648
Abstract: Pregnane X receptor (PXR) is a ligandâactivated nuclear receptor (NR) that was originally identified as a master regulator of xenobiotic detoxification. It regulates the expression of drugâmetabolizing enzymes and transporters to control the degradation and… read more here.
Keywords: metabolism; drug; pxr; pregnane receptor ... See more keywords