Comparative genomics analysis of statistically significant genomic islands of Helicobacter pylori strains for better understanding the disease prognosis
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DOI: 10.1042/bsr20212084
Abstract: Abstract Bacterial virulence factors are often located in their genomic islands (GIs). Helicobacter pylori, a highly diverse organism is reported to be associated with several gastrointestinal diseases like, gastritis, gastric cancer (GC), peptic ulcer, duodenal… read more here.
Keywords: better understanding; pylori strains; disease prognosis; virulence ... See more keywords
Antibiotic resistance pattern of Helicobacter pylori strains isolated in Italy during 2010–2016
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DOI: 10.1080/00365521.2018.1464596
Abstract: Abstract Purpose: Bacterial resistance toward the most used antibiotics is increasing in Helicobacter pylori strains worldwide. Emergence of multidrug resistance significantly affects the efficacy of standard therapy regimens. Therefore, monitoring for primary antimicrobial resistance is… read more here.
Keywords: clarithromycin metronidazole; pylori strains; 2010 2016; resistance ... See more keywords
BabA-mediated adherence of pediatric ulcerogenic H. pylori strains to gastric mucins at neutral and acidic pH
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DOI: 10.1080/21505594.2018.1532243
Abstract: ABSTRACT Helicobacter pylori infection can result in non-ulcer dyspepsia (NUD), peptic ulcer disease (PUD), adenocarcinoma, and gastric lymphoma. H. pylori reside within the gastric mucus layer, mainly composed of mucins carrying an array of glycan… read more here.
Keywords: pylori strains; baba positive; gastric mucins; neutral acidic ... See more keywords
The outward shift of clarithromycin binding to the ribosome in mutant Helicobacter pylori strains
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DOI: 10.1111/hel.12731
Abstract: Disruption of protein synthesis, by drug‐mediated restriction of the ribosomal nascent peptide exit tunnel (NPET), may inhibit bacterial growth. Here, we have studied the secondary and tertiary structures of domain V of the 23S rRNA… read more here.
Keywords: shift clarithromycin; outward shift; pylori strains; helicobacter ... See more keywords
Establishment of a reference panel of Helicobacter pylori strains for antimicrobial susceptibility testing
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DOI: 10.1111/hel.12874
Abstract: Eradication treatment for Helicobacter pylori gastritis is covered by national health insurance since 2013 in Japan. However, eradication failure due to the increase of antimicrobial resistance has become a serious problem. The present study aims… read more here.
Keywords: pylori strains; reference panel; helicobacter; strains antimicrobial ... See more keywords
Genetic signatures for Helicobacter pylori strains of West African origin
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DOI: 10.1371/journal.pone.0188804
Abstract: Helicobacter pylori is a genetically diverse bacterial species that colonizes the stomach in about half of the human population. Most persons colonized by H. pylori remain asymptomatic, but the presence of this organism is a… read more here.
Keywords: african origin; west african; pylori strains; genetic signatures ... See more keywords
Multidrug-Resistant Helicobacter pylori Strains: A Five-Year Surveillance Study and Its Genome Characteristics
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DOI: 10.3390/antibiotics11101391
Abstract: Background: The emergence of multidrug-resistant Helicobacter pylori has undermined eradication strategies to prevent the development of gastric cancer. This study was conducted to estimate the prevalence of secondary antibiotic resistance of H. pylori in urban… read more here.
Keywords: pylori strains; resistance; multidrug resistant; resistant helicobacter ... See more keywords
A Comparative Study on Nickel Binding to Hpn-like Polypeptides from Two Helicobacter pylori Strains
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DOI: 10.3390/ijms222413210
Abstract: Combined potentiometric titration and isothermal titration calorimetry (ITC) methods were used to study the interactions of nickel(II) ions with the N-terminal fragments and histidine-rich fragments of Hpn-like protein from two Helicobacter pylori strains (11637 and… read more here.
Keywords: nickel binding; hpn like; binding hpn; pylori strains ... See more keywords
Geographically Distinct North-East Indian Helicobacter pylori Strains are Highly Sensitive to Clarithromycin but are Levofloxacin Resistant.
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DOI: 10.4103/ijmm.ijmm_19_158
Abstract: PURPOSE Helicobacter pylori causes various gastro-intestinal diseases. Antibiotic resistance to commonly used antibiotics for the treatment of H. pylori infection is the major cause for treatment failure. The aim of this study is to determine… read more here.
Keywords: north east; east indian; pylori strains; clarithromycin levofloxacin ... See more keywords